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Associations between skin rash, treatment outcome, and single nucleotide poly...
Purpose: To study the associations between development of moderate to severe skin rash, clinical outcome, and single nucleotide polymorphisms (SNPs) in candidate genes in head... -
A study on the safety and efficacy of reveglucosidase alfa in patients with l...
Background Late-onset Pompe disease is a rare genetic neuromuscular disorder caused by lysosomal acid alpha-glucosidase (GAA) deficiency that ultimately results in mobility loss... -
Blood-flow restricted resistance training in patients with sporadic inclusion...
Objectives: To investigate the effect of 12 weeks of low-load blood-flow restricted resistance (BFR) training on self-reported and objective physical function, and maximal... -
Broad phenotypic spectrum and genotype-phenotype correlations in GMPPB-relate...
Background Dystroglycanopathy (α-DG) is a relatively common, clinically and genetically heterogeneous category of congenital forms of muscular dystrophy (CMD) and limb-girdle... -
Privacy Attitudes among Early Adopters of Emerging Health Technologies
Introduction Advances in health technology such as genome sequencing and wearable sensors now allow for the collection of highly granular personal health data from individuals.... -
"Expanded HIV Testing in Low-Prevalence, High-Income Countries: A Cost-Effect...
Objective In many high-income countries with low HIV prevalence, significant numbers of persons living with HIV (PLHIV) remain undiagnosed. Identification of PLHIV via HIV... -
Publication pressure and burn out among Dutch medical professors: a nationwid...
BACKGROUND: Publication of scientific research papers is important for professionals working in academic medical centres. Quantitative measures of scientific output determine... -
"How much will I get charged for this?" Patient charges for top ten diagnoses...
Objectives We examined the charges, their variability, and respective payer group for diagnosis and treatment of the ten most common outpatient conditions presenting to the... -
Development and validation of a prognostic model for recurrent glioblastoma p...
Background Predictive markers and prognostic models are required in order to individualize treatment of recurrent glioblastoma (GBM) patients. Here, we sought to identify... -
Health-related quality of life in rectal cancer patients undergoing neoadjuva...
Background: Neoadjuvant chemoradiation with delayed surgery (CRT-DS) and short-course radiotherapy with immediate surgery (SCRT-IS) are two commonly used treatment strategies... -
Trends in alcohol use among young people according to the pattern of consumpt...
Aim To identify differences in Risky Consumption (RC) and Binge drinking (BD) trends in students who already followed these patterns of alcohol consumption on starting... -
Crowd-figure-pictograms improve women’s knowledge about mammography screening...
Objective To evaluate the effect of crowd-figure-pictograms on women’s numeric knowledge about mammography screening in a three-armed parallel randomised controlled trial.... -
The effect of postoperative gemcitabine on overall survival in patients with ...
Background: Adjuvant chemotherapy following curative resection is the standard treatment for pancreatic adenocarcinoma (PC). Randomized clinical trials using gemcitabine have... -
Cilostazol induced migraine does not respond to sumatriptan in a double blind...
Background Cilostazol is an inhibitor of phosphodiesterase 3 and thus causes accumulation of cAMP. It induces migraine-like attacks in migraine patients. Whether the cilostazol... -
Defining a core outcome set for adolescent and young adult patients with a sp...
Background and purpose - Routine outcome measurement has been shown to improve performance in several fields of healthcare. National spine surgery registries have been initiated... -
Efficacy of a New Educational Tool to Improve Handrubbing Technique amongst H...
INTRODUCTION: Hand hygiene is a key component of infection control in healthcare. WHO recommends that healthcare workers perform six specific poses during each hand hygiene... -
Patients Are Paying Too Much for Tuberculosis: A Direct Cost-Burden Evaluatio...
Paying for health care may exclude poor people. Burkina Faso adopted the DOTS strategy implementing "free care" for Tuberculosis (TB) diagnosis and treatment. This should... -
Defining Catastrophic Costs and Comparing Their Importance for Adverse Tuberc...
Tom Wingfield and colleagues investigate the relationship between catastrophic costs and tuberculosis outcomes for patients receiving free tuberculosis care in Peru. Please see... -
Physical activity levels of women with breast cancer during and after treatme...
Background: Physical activity has been shown to reduce side-effects of breast cancer and its treatment. As physical activity levels of patients with breast cancer are largely... -
Sphenopalatine ganglion stimulation for cluster headache, results from a larg...
Background Cluster headache (CH) is a disabling primary headache disorder characterized by severe periorbital pain. A subset of patients does not respond to established...
