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Dried blood spot versus venous blood sampling for phenylalanine and tyrosine
Abstract Background This study investigated the agreement between various dried blood spot (DBS) and venous blood sample measurements of phenylalanine and tyrosine... -
Erythropoietin as an add-on treatment for cognitive side effects of electroco...
Abstract Background Electroconvulsive therapy (ECT) is the most effective treatment for severe depression, but its use is impeded by its cognitive side effects. Novel treatments... -
Omalizumab in patients with severe asthma and persistent sputum eosinophilia
Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who... -
Serum progesterone distribution in normal pregnancies compared to pregnancies...
Abstract Background Progesterone is a critical hormone in early pregnancy. A low level of serum progesterone is associated with threatened miscarriage. We aim to establish the... -
Comparative analyses of the in vivo induction and transmission of α-synuclein...
Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central... -
Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate...
Abstract Background Dexketoprofen trometamol plus tramadol hydrochloride is a new oral combination of two analgesics, which have different mechanisms of action for the treatment... -
Hemostatic effect of tourniquet combined with tranexamic acid in total knee a...
Abstract Background There are various techniques to reduce blood loss in total knee arthroplasty (TKA), including the use of a tourniquet and tranexamic acid (TXA). In this... -
A modulatory role of ASICs on GABAergic synapses in rat hippocampal cell cult...
Abstract Rapid acidification occurring during synaptic vesicle release can activate acid-sensing ion channels (ASICs) both on pre- and postsynaptic neurons. In the latter case,... -
Altered functional connectivity of the nucleus accumbens subdivisions in amph...
Abstract Background The growing abuse of amphetamine-type stimulants leads to new challenges to human health. A possible addiction mechanism has been proposed by altered... -
Gout is not associated with the risk of fracture: a meta-analysis
Abstract Background Numerous quantitatively based studies measuring the association between gout and the risk of fractures remain inconclusive. In order to determine whether... -
Combination of Ranibizumab with macular laser for macular edema secondary to ...
Abstract Background It is not clear whether macular laser combined with anti-vascular endothelial growth factor (VEGF) can reduce the number of anti-VEGF injections in the... -
Possible beneficial association between renin-angiotensin-aldosterone-system ...
Abstract Background Although immunoglobulin A nephropathy (IgAN) is associated with an increased risk of renal allograft failure, evidences for its treatment, including... -
ConFIRM trial - conversion of in vitro fertilization cycles to intrauterine i...
Abstract Background To date, there is no consensus on the ideal management strategy of patients with poor ovarian response (POR) to controlled ovarian stimulation (COS) for in... -
Knowledge and attitudes about transcranial magnetic stimulation among psychia...
Abstract Background Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive form of brain stimulation. It has been used in many mental health institutions to treat... -
Effects of external application of compound Qingbi granules on acute gouty ar...
Abstract Background and aim The use of anti-inflammatory and analgesic drugs such as nonsteroidal anti-inflammatory drugs(NSAIDs) for treating acute gout has limitations, such... -
cAMP- and cGMP-elevating agents inhibit GPIbα-mediated aggregation but not GP...
Abstract Background The glycoprotein (GP) Ib-IX-V complex is a unique platelet plasma membrane receptor, which is essential for platelet adhesion and thrombus formation. GPIbα,... -
ERα-36 regulates progesterone receptor activity in breast cancer
Abstract Background Alterations in estrogen and progesterone signaling, via their respective receptors, estrogen receptor alpha (ERα) and progesterone receptor (PR),... -
Highly active promoters and native secretion signals for protein production d...
Abstract Background The filamentous ascomycete Aspergillus niger is used in many industrial processes for the production of enzymes and organic acids by batch and fed-batch... -
Strain Effect on Thermoelectric Performance of InSe Monolayer
Abstract Strain engineering is a practical method to tune and improve the physical characteristics and properties of two-dimensional materials, due to their large... -
Effects of cyclosporine A pretreatment of deceased organ donors on kidney gra...
Abstract Background Renal transplantation represents the treatment of choice of end-stage kidney disease. Delayed graft function (DGF) remains the most frequent complication...
