-
Dried blood spot versus venous blood sampling for phenylalanine and tyrosine
Abstract Background This study investigated the agreement between various dried blood spot (DBS) and venous blood sample measurements of phenylalanine and tyrosine... -
Erythropoietin as an add-on treatment for cognitive side effects of electroco...
Abstract Background Electroconvulsive therapy (ECT) is the most effective treatment for severe depression, but its use is impeded by its cognitive side effects. Novel treatments... -
Pleural effusion from intrathoracic migration of a ventriculo-peritoneal shun...
Abstract Background Pleural effusion is a rare complication of ventriculo-peritoneal (VP) cerebrospinal fluid (CSF) shunting and its diagnosis is difficult in patients with... -
Comparative analyses of the in vivo induction and transmission of α-synuclein...
Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central... -
French lyophilized plasma versus normal saline for post-traumatic coagulopath...
Abstract Background Post-trauma bleeding induces an acute deficiency in clotting factors, which promotes bleeding and hemorrhagic shock. However, early plasma administration may... -
Microcirculatory dysfunction and dead-space ventilation in early ARDS: a hypo...
Abstract Background Ventilation/perfusion inequalities impair gas exchange in acute respiratory distress syndrome (ARDS). Although increased dead-space ventilation (VD/VT) has... -
The validity of pediatric cancer diagnoses in a population-based general canc...
Abstract Background Data from population-based cancer registries are increasingly used to conduct research and guide policy. However, few validation studies of cancer registry... -
Low levels of pyruvate induced by a positive feedback loop protects cholangio...
Abstract Background Cancer cells avidly consume glucose and convert it to lactate, resulting in a low pyruvate level. This phenomenon is known as the Warburg effect, and is... -
Long-term Safety and Efficacy of Human-Induced Pluripotent Stem Cell (iPS) Gr...
Abstract The U.S. Food and Drug Administration recently approved phase I/II clinical trials for embryonic stem (ES) cell-based retinal pigmented epithelium (RPE)... -
Measuring influenza laboratory capacity: use of a tool to measure improvements
Abstract Background To collect information, identify training needs, and assist with influenza capacity building voluntary laboratory capacity assessments were conducted using a... -
Perioperative surgery- and anaesthesia-related risks of laparoscopic Roux-en-...
Abstract Background Conservative obesity treatment often leads to limited results. Bariatric surgery is highly efficient, but the candidates are at risk of developing... -
Quality of life in elderly people after a hip fracture: a prospective study
Abstract Background Hip fracture is an important social and medical problem due to its increasing prevalence, the consequences for health and the economic impact on the health... -
Assessment of research waste part 1: an exemplar from examining study design,...
Abstract Background Research waste is estimated to be very common, but assessments of its prevalence and scope are rare. As an example, we assessed research waste in clinical... -
Ablation of epidermal RXRα in cooperation with activated CDK4 and oncogenic N...
Abstract Background Understanding the underlying molecular mechanisms involved in the formation of cutaneous malignant melanoma is critical for improved diagnosis and treatment.... -
cAMP- and cGMP-elevating agents inhibit GPIbα-mediated aggregation but not GP...
Abstract Background The glycoprotein (GP) Ib-IX-V complex is a unique platelet plasma membrane receptor, which is essential for platelet adhesion and thrombus formation. GPIbα,... -
Circulating PCSK9 and cardiovascular events in FH patients with standard lipi...
Abstract Background Proprotein convertase subtilisin/kexin 9 (PCSK9) has been proposed as a novel target for coronary artery disease (CAD). Familial hypercholesterolemia (FH) is... -
HORN-6 special-purpose clustered computing system for electroholography
We developed the HORN-6 special-purpose computer for holography. We designed and constructed the HORN-6 board to handle an object image composed of one million points and... -
The putative β-glucosidase BGL3I regulates cellulase induction in Trichoderma...
Abstract Background The filamentous fungus Trichoderma reesei (anamorph of Hypocrea jecorina) displays increased cellulase expression while growing on inducers such as lactose... -
Clinical guidelines for the management of treatment-resistant depression: Fre...
Abstract Background Clear guidance for successive antidepressant pharmacological treatments for non-responders in major depression is not well established. Method Based on the... -
Core Rehabilitation Outcome Set for Single Sided Deafness (CROSSSD) study: pr...
Abstract Background Single-sided deafness (SSD) describes the presence of a unilateral severe to profound sensorineural hearing loss. SSD disrupts spatial hearing and...
