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A novel transcription factor specifically regulates GH11 xylanase genes in Tr...
Abstract Background The filamentous fungus Trichoderma reesei is widely utilized in industry for cellulase production, but its xylanase activity must be improved to enhance the... -
Module and individual domain deletions of NRPS to produce plipastatin derivat...
Abstract Background Plipastatin, an antifungal lipopeptide, is synthesized by a non-ribosomal peptide synthetase (NRPS) in Bacillus subtilis. However, little information is... -
The putative β-glucosidase BGL3I regulates cellulase induction in Trichoderma...
Abstract Background The filamentous fungus Trichoderma reesei (anamorph of Hypocrea jecorina) displays increased cellulase expression while growing on inducers such as lactose... -
Fecal metatranscriptomics of macaques with idiopathic chronic diarrhea reveal...
Abstract Background Idiopathic chronic diarrhea (ICD) is a common cause of morbidity and mortality among juvenile rhesus macaques. Characterized by chronic inflammation of the... -
Prediction of advanced colonic neoplasm in symptomatic patients: a scoring sy...
Abstract Background Fast-track colonoscopy to detect patients with colorectal cancer based on high-risk symptoms is associated with low sensitivity and specificity. The aim was... -
Reference genome and comparative genome analysis for the WHO reference strain...
The BCG live attenuated TB vaccine is one of the oldest and most widely used vaccines in human medicine. Each year, BCG vaccines are administered to over 100 million newborns... -
Construction of a trifunctional cellulase and expression in Saccharomyces cer...
Abstract Background Cellulose is the most important component of lignocellulose, and its degradation requires three different types of enzymes to act synergistically. There have... -
A toolset of constitutive promoters for metabolic engineering of Rhodosporidi...
Abstract Background Rhodosporidium toruloides is a promising host for the production of bioproducts from lignocellulosic biomass. A key prerequisite for efficient pathway... -
Optimization of cellulolytic enzyme components through engineering Trichoderm...
Abstract Background Cellulolytic enzymes produced by Trichoderma reesei are widely studied for biomass bioconversion, and enzymatic components vary depending on different... -
Improving squalene production by enhancing the NADPH/NADP+ ratio, modifying t...
Abstract Background Squalene is currently used widely in the food, cosmetics, and medicine industries. It could also replace petroleum as a raw material for fuels. Microbial... -
The index of prediction accuracy: an intuitive measure useful for evaluating ...
Abstract Background Many measures of prediction accuracy have been developed. However, the most popular ones in typical medical outcome prediction settings require additional... -
Development of a Microsoft Excel tool for applying a factor retention criteri...
Abstract Background Many quality-of-life studies have been conducted in healthcare settings, but few have used Microsoft Excel to incorporate Cronbach’s α with dimension... -
An efficient modified method for plant leaf lipid extraction results in impro...
Abstract Background Lipidomics plays an important role in understanding plant adaptation to different stresses and improving our knowledge of the genes underlying lipid... -
The Ussing chamber system for measuring intestinal permeability in health and...
Abstract Background The relationship between intestinal epithelial integrity and the development of intestinal disease is of increasing interest. A reduction in mucosal... -
Chromosomal integration vectors allowing flexible expression of foreign genes...
Abstract Background Campylobacter jejuni is a major cause of human gastroenteritis yet there is limited knowledge of how disease is caused. Molecular genetic approaches are... -
Enzyme adsorption-induced activity changes: a quantitative study on TiO2 mode...
Abstract Background Activity retention upon enzyme adsorption on inorganic nanostructures depends on different system parameters such as structure and composition of the... -
Bi-Assisted CdTe/CdS Hierarchical Nanostructure Growth for Photoconductive Ap...
Abstract We developed a method to control the structure of CdTe nanowires by adopting Bi-mixed CdTe powder source to a catalyst-assisted chemical vapor deposition, which allowed... -
Synthetic control devices for gene regulation in Penicillium chrysogenum
Abstract Background Orthogonal, synthetic control devices were developed for Penicillium chrysogenum, a model filamentous fungus and industrially relevant cell factory. In the... -
Efficient and mild swern oxidation using a new sulfoxide and <i>bis</i>(trich...
A new type of sulfoxide, 4-(2-(2-(methylsulfinyl) ethyl)-4-nitrophenyl)- morpholine (I) was designed and prepared in good yield. Upon the combination of I andbis... -
Porphyrins are increased in the faeces of patients with prostate cancer: a ca...
Abstract Background Experimental models of prostate cancer have demonstrated increased levels of protoporphyrin IX (PpIX) in the blood and faeces of mice. Hence, the...
