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On-demand virtual optical network access using 100 Gb/s Ethernet
Our Terabit LAN initiatives attempt to enhance the scalability and utilization of lambda resources. This paper describes bandwidth-on-demand virtualized 100GE access to WDM... -
CDKAM: a taxonomic classification tool using discriminative k-mers and approx...
Abstract Background Current taxonomic classification tools use exact string matching algorithms that are effective to tackle the data from the next generation sequencing... -
Cnidaria: fast, reference-free clustering of raw and assembled genome and tra...
Abstract Background Identification of biological specimens is a requirement for a range of applications. Reference-free methods analyse unprocessed sequencing data without... -
Millstone: software for multiplex microbial genome analysis and engineering
Abstract Inexpensive DNA sequencing and advances in genome editing have made computational analysis a major rate-limiting step in adaptive laboratory evolution and microbial... -
Horizontal gene transfer is not a hallmark of the human genome
Abstract Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al. as... -
Use of scientific social networking to improve the research strategies of Pub...
Abstract Background Keeping up with journal articles on a daily basis is an important activity of scientists engaged in biomedical research. Usually, journal articles and papers... -
Fast dimension reduction and integrative clustering of multi-omics data using...
Abstract Background One major goal of large-scale cancer omics study is to identify molecular subtypes for more accurate cancer diagnoses and treatments. To deal with... -
Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns u...
Abstract Background Claudin-low breast cancer is a molecular subtype associated with poor prognosis and without targeted treatment options. The claudin-low subtype is defined by... -
FORGe: prioritizing variants for graph genomes
Abstract There is growing interest in using genetic variants to augment the reference genome into a graph genome, with alternative sequences, to improve read alignment accuracy... -
Surmounting obstacles by arm maneuver for unmanned power shovel
Abstract Large debris created after natural disasters restrict access to inner parts of affected regions, and slows down disaster relief operations. Power shovels are often used... -
Gene expression analysis of potential morphogen signalling modifying factors ...
Abstract Background Morphogen signalling represents a key mechanism of developmental processes during animal development. Previously, several evolutionary conserved morphogen... -
Evaluation of whole exome sequencing as an alternative to BeadChip and whole ...
Abstract Background Understanding the underlying genetic structure of human populations is of fundamental interest to both biological and social sciences. Advances in... -
Educational Action Research and Triple Helix principles in entrepreneurship e...
Abstract This article presents a practical approach on how to develop and explore an educational design combining Triple Helix theory and Educational Action Research for support... -
GAPPadder: a sensitive approach for closing gaps on draft genomes with short ...
Abstract Background Closing gaps in draft genomes is an important post processing step in genome assembly. It leads to more complete genomes, which benefits downstream genome... -
Wnt signal transduction pathways: modules, development and evolution
Abstract Background Wnt signal transduction pathway (Wnt STP) is a crucial intracellular pathway mainly due to its participation in important biological processes, functions,... -
G-DOC Plus â an integrative bioinformatics platform for precision medicine
Abstract Background G-DOC Plus is a data integration and bioinformatics platform that uses cloud computing and other advanced computational tools to handle a variety of... -
RBLOSUM performs better than CorBLOSUM with lesser error per query
Abstract Objective BLOSUM matrices serve as standard matrices for many protein sequence alignment programs. BLOSUM matrices have been constructed using BLOCKS version5.0 with... -
Structural and mechanistic analysis of engineered trichodiene synthase enzyme...
Trichoderma spp. are well-known bioagents for the plant growth promotion and pathogen suppression. The beneficial activities of the fungus Trichoderma spp. are attributed to... -
MPBoot: fast phylogenetic maximum parsimony tree inference and bootstrap appr...
Abstract Background The nonparametric bootstrap is widely used to measure the branch support of phylogenetic trees. However, bootstrapping is computationally expensive and... -
PyPedia: using the wiki paradigm as crowd sourcing environment for bioinforma...
Abstract Background Today researchers can choose from many bioinformatics protocols for all types of life sciences research, computational environments and coding languages....
