-
A description of sleep behaviour in healthy late pregnancy, and the accuracy ...
Abstract Background The importance of maternal sleep and its contribution to maternal and fetal health during pregnancy is increasingly being recognised. However, the ability to... -
Resveratrol mediates mechanical allodynia through modulating inflammatory res...
Abstract Background Neuropathic pain (NeuP) is a chronic and challenging clinical problem, with little effective treatment. Resveratrol has shown neuroprotection by inhibiting... -
Endovascular external carotid artery occlusion for brain selective targeting:...
Abstract Background The choice of an animal model for cerebrovascular research is often determined by the disease subtype to be studied (e.g. ischemic stroke, hemorrhage,... -
The potassium channel KCa3.1 represents a valid pharmacological target for mi...
Abstract Background Recent studies described a critical role for microglia in Parkinson’s disease (PD), where these central nerve system resident immune cells participate in the... -
INSPECT: extending plane-casting for 6-DOF control
Abstract INSPECT is a novel interaction technique for 3D object manipulation using a rotation-only tracked touch panel. Motivated by the applicability of the technique on... -
Exploring physiological signals on people with Duchenne muscular dystrophy fo...
Abstract Background Arm support devices are available to support people with Duchenne muscular dystrophy (DMD), but active trunk support devices are lacking. An active trunk... -
Comparison of gray matter volume between migraine and "strict-criteria" tensi...
Abstract Background Despite evidently distinct symptoms, tension-type headache (TTH) and migraine are highly comorbid and exhibit many similarities in clinical practice. The... -
Lipopolysaccharide-induced neuroinflammation induces presynaptic disruption t...
Abstract Background Systemic inflammation has been linked to synapse loss and cognitive decline in human patients and animal models. A role for microglial release of... -
Survey of maternal sleep practices in late pregnancy in a multi-ethnic sample...
Abstract Background The Auckland Stillbirth study demonstrated a two-fold increased risk of late stillbirth for women who did not go to sleep on their left side. Two further... -
Ex vivo model of epilepsy in organotypic slices—a new tool for drug screening
Abstract Background Epilepsy is a prevalent neurological disorder worldwide. It is characterized by an enduring predisposition to generate seizures and its development is... -
Teaching young GPs to cope with psychosocial consultations without prescribin...
Abstract Background Despite guidelines and campaigns to change prescribing behavior, General Practitioners (GPs) continue to overprescribe benzodiazepines (BZDs). New approaches... -
Longitudinal changes in desired body weight compared to changes in body weigh...
Abstract Background Overweight individuals desire a lower weight than they actually have. Little is known on the extent to which this discrepancy is reduced over time due to... -
Microglia P2X4 receptor contributes to central sensitization following recurr...
Abstract Background The mechanism underlying migraine chronification remains unclear. Central sensitization may account for this progression. The microglia P2X4 receptor (P2X4R)... -
Patterns of health behaviour associated with active travel: a compositional d...
Abstract Background Active travel (walking or cycling for transport) is associated with favourable health outcomes in adults. However, little is known about the concurrent... -
Evaluation of two collagen conduits and autograft in rabbit sciatic nerve reg...
Abstract Background We compared different surgical techniques for nerve regeneration in a rabbit sciatic nerve gap model using magnetic resonance diffusion tensor imaging (DTI),... -
Epigenetic suppression of liver X receptor β in anterior cingulate cortex by ...
Abstract Background Liver X receptors (LXRs), including LXRα and LXRβ, are key regulators of transcriptional programs for both cholesterol homeostasis and inflammation in the... -
Ready, Set, Change! Development and usability testing of an online readiness ...
Abstract Background To address challenges related to selecting a valid, reliable, and appropriate readiness assessment measure in practice, we developed an online decision... -
Expression and activity of the calcitonin receptor family in a sample of prim...
Abstract Background Glioblastoma (GBM) is the most common and aggressive type of primary brain cancer. With median survival of less than 15â months, identification and... -
Suppression of MyD88-dependent signaling alleviates neuropathic pain induced ...
Abstract Background MyD88 is the adaptor protein of MyD88-dependent signaling pathway of TLRs and IL-1 receptor and regulates innate immune response. However, it was not clear... -
Crosstalk between NFκB-dependent astrocytic CXCL1 and neuron CXCR2 plays a ro...
Abstract Background Despite accumulating evidence on the role of glial cells and their associated chemicals in mechanisms of pain, few studies have addressed the potential role...
