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Symptoms in Swiss adolescents in relation to exposure from fixed site transmi...
Abstract Background There is public concern regarding potential health effects of radiofrequency electromagnetic fields (RF-EMF) emitted by fixed site transmitters. We therefore... -
A novel transcription factor specifically regulates GH11 xylanase genes in Tr...
Abstract Background The filamentous fungus Trichoderma reesei is widely utilized in industry for cellulase production, but its xylanase activity must be improved to enhance the... -
Consensus of potential modifiable prognostic factors for persistent pain afte...
Abstract Background Identify and establish consensus regarding potential prognostic factors for the development of chronic pain after a first episode of idiopathic,... -
TSS seq based core promoter architecture in blood feeding Tsetse fly (Glossin...
Abstract Background Transcription initiation regulation is mediated by sequence-specific interactions between DNA-binding proteins (transcription factors) and cis-elements,... -
Delay in diagnosis of pulmonary tuberculosis increases the risk of pulmonary ...
Abstract Background Delay in diagnosis and treatment of pulmonary tuberculosis (PTB) leads to severe disease, adverse outcomes and increased transmission. Assessing the extent... -
A novel pyruvate kinase and its application in lactic acid production under o...
Abstract Background Pyruvate kinase (Pyk) catalyzes the generation of pyruvate and ATP in glycolysis and functions as a key switch in the regulation of carbon flux distribution.... -
miRNA alteration is an important mechanism in sugarcane response to low-tempe...
Abstract Background Cold is a major abiotic stress limiting the production of tropical and subtropical crops in new production areas. Sugarcane (Saccharum spp.) originates from... -
Development and validation of a variant detection workflow for BRCA1 and BRCA...
Abstract Background Breast cancer is the most common among women worldwide, and ovarian cancer is the most difficult gynecological tumor to diagnose and with the lowest chance... -
Polygenic risk for coronary heart disease acts through atherosclerosis in typ...
Abstract Background Type 2 diabetes increases the risk of coronary heart disease (CHD), yet the mechanisms involved remain poorly described. Polygenic risk scores (PRS) provide... -
Identification and validation of a Schistosoma japonicum U6 promoter
Abstract Background RNA polymerase III promoters have been widely used to express short hairpin-RNA (shRNA), microRNA (miRNA), and small guide RNA (sgRNA) in gene functional... -
Regulatory role of microRNA in mesenteric lymph nodes after Salmonella Typhim...
Abstract Salmonellosis is a gastrointestinal disease caused by non-typhoidal Salmonella serovars such as Salmonella Typhimurium. This pathology is a zoonosis, and food animals... -
Chromosomal integration vectors allowing flexible expression of foreign genes...
Abstract Background Campylobacter jejuni is a major cause of human gastroenteritis yet there is limited knowledge of how disease is caused. Molecular genetic approaches are... -
Independent modulation of individual genomic component transcription and a ci...
Abstract Background The genome of Banana bunchy top virus (BBTV) consists of at least six circular, single-stranded DNA components of ~ 1 kb in length. Some BBTV isolates may... -
Optical stretching of giant unilamellar vesicles with an integrated dual-beam...
We have integrated a dual-beam optical trap into a microfluidic platform and used it to study membrane mechanics in giant unilamellar vesicles (GUVs). We demonstrate the... -
Bidirectional promoters exhibit characteristic chromatin modification signatu...
Abstract Background In contrast to unidirectional promoters wherein antisense transcription results in short transcripts which are rapidly degraded, bidirectional promoters... -
Capturing pharmacists’ impact in general practice: an e-Delphi study to attem...
Abstract Background In the UK, there is ongoing integration of pharmacists into general practice as a new healthcare service in primary care. Evaluation of the service involves... -
Inherent bacterial DNA contamination of extraction and sequencing reagents ma...
Abstract Background The advent and use of highly sensitive molecular biology techniques to explore the microbiota and microbiome in environmental and tissue samples have... -
Prevalence of G6PD deficiency and Plasmodium falciparum parasites in asymptom...
Abstract Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked genetic disorder that results in impaired enzyme activity. Although G6PD deficiency is... -
The impact of occupational and personal factors on musculoskeletal pain - a c...
Abstract Background Musculoskeletal pain is common in the general population and constitutes a major public health problem. A large proportion of these conditions may be work... -
Transcriptomic and phosphoproteomic profiling and metabolite analyses reveal ...
Abstract Background Organic acid secretion is a widespread physiological response of plants to alkalinity. However, the characteristics and underlying mechanism of the...
