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MRI of trunk muscles and motor and respiratory function in patients with myot...
Abstract Background Myotonic Dystrophy 1 (DM1) causes progressive myopathy of extremity muscles. DM1 may also affect muscles of the trunk. The aim of this study was to... -
Advanced paternal age as a risk factor for neurodevelopmental disorders: a tr...
Abstract Advanced paternal age (APA) is a risk factor for several neurodevelopmental disorders, including autism and schizophrenia. The potential mechanisms conferring this risk... -
Autonomic nervous system response to remote ischemic conditioning: heart rate...
Abstract Background Remote ischemic conditioning (RIC) is a procedure applied in a limb for triggering endogenous protective pathways in distant organs, namely brain or heart.... -
Ca2+ in the dorsal raphe nucleus promotes wakefulness via endogenous sleep-wa...
Abstract Serotonergic neurons in the dorsal raphe nucleus (DRN) are involved in the control of sleep-wake states. Our previous studies have indicated that calcium (Ca2+)... -
Comparative analyses of the in vivo induction and transmission of α-synuclein...
Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central... -
Nanomedicine-driven neuropathic pain relief in a rat model is associated with...
Abstract We explored the immune neuropathology underlying multi-day relief from neuropathic pain in a rat model initiated at the sciatic nerve, by using a nanoemulsion-based... -
Peripheral cathepsin L inhibition induces fat loss in C. elegans and mice thr...
Abstract Background Cathepsin L and some other cathepsins have been implicated in the development of obesity in humans and mice. The functional inactivation of the proteases... -
Immediate effects of a lumbar spine manipulation on pain sensitivity and post...
Abstract Background According to the American Physical Therapy Association, there is strong evidence to show that vertebral mobilization and manipulation procedures can be used... -
Factors influencing decision regret regarding placement of a PEG among substi...
Abstract Background A tube feeding decision aid designed at the Ottawa Health Research Institute was specifically created for substitute decision-makers who must decide whether... -
Effects of methylprednisolone on blood-brain barrier and cerebral inflammatio...
Abstract Background Cognitive dysfunction is a frequent complication to open-heart surgery. Cerebral inflammation caused by blood-brain barrier (BBB) dysfunction due to a... -
Pain rates in general population for the period 1991–2015 and 10-years predic...
Abstract Background Pain is a common symptom, often associated with neurological and musculoskeletal conditions, and experienced especially by females and by older people. The... -
Contacting out-of-hours primary care or emergency medical services for time-c...
Abstract Background Out-of-hours (OOH) healthcare services in Western countries are often differentiated into out-of-hours primary healthcare services (OOH-PC) and emergency... -
Parkin deficiency prevents chronic ethanol-induced hepatic lipid accumulation...
Abstract Background Alcohol abuse and alcoholism lead to alcohol liver disease such as alcoholic fatty liver. Parkin is a component of the multiprotein E3 ubiquitin ligase... -
A mathematical model provides mechanistic links to temporal patterns in Droso...
Abstract Background Circadian clocks are endogenous biochemical oscillators that control daily behavioral rhythms in all living organisms. In fruit fly, the circadian rhythms... -
The association between socioeconomic status and visual impairments among pri...
Abstract Background Glaucoma is one of the most leading causes of permanent visual impairments in Korea, and social expenses spent for the glaucoma are increasing. This study is... -
Postoperative analgesia of scalp nerve block with ropivacaine in pediatric cr...
Abstract Background Moderate-to-severe postoperative pain following craniotomy has a high incidence in pediatric patients. Such pain may cause agitation, intracranial... -
Prenatal smoking exposure and neuropsychiatric comorbidity of ADHD: a finnish...
Abstract Background Prenatal smoking exposure has been associated with attention-deficit/hyperactivity disorder (ADHD). ADHD is commonly associated with a wide spectrum of... -
ADHD-related symptoms and attention profiles in the unaffected siblings of pr...
Abstract Background The presence of attention-deficit/hyperactive disorder (ADHD) symptoms and impaired attention performance are commonly noted in individuals with autism... -
Yy1 regulates Senp1 contributing to AMPA receptor GluR1 expression following ...
Abstract Background Neuronal activity-induced changes in gene expression patterns are important mediators of neuronal plasticity. Many neuronal genes can be activated or... -
Matured hop extract reduces body fat in healthy overweight humans: a randomiz...
Abstract Background Hops are the main components of beer that provide flavor and bitterness. Iso-α-acids, the bitter components of beer, have been reported to reduce body fat in...
