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Continue, adjust, or stop antipsychotic medication: developing and user testi...
Abstract Background People with psychosis struggle with decisions about their use of antipsychotics. They often want to reduce the dose or stop, while facing uncertainty... -
MRI of trunk muscles and motor and respiratory function in patients with myot...
Abstract Background Myotonic Dystrophy 1 (DM1) causes progressive myopathy of extremity muscles. DM1 may also affect muscles of the trunk. The aim of this study was to... -
A pilot feasibility randomised controlled trial of an adjunct brief social ne...
Abstract Background Approximately 3% of people receiving opioid substitution therapy (OST) in the UK manage to achieve abstinence from prescribed and illicit drugs within three... -
Erythropoietin as an add-on treatment for cognitive side effects of electroco...
Abstract Background Electroconvulsive therapy (ECT) is the most effective treatment for severe depression, but its use is impeded by its cognitive side effects. Novel treatments... -
The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzhe...
Abstract Background Synaptic degeneration is a central pathogenic event in Alzheimer’s disease that occurs early during the course of disease and correlates with cognitive... -
A meta-analysis of depressive symptoms among Ethiopian prisoners and a narrat...
Abstract Background The burden of depression in prisoners is increasing and factors such as co-existence of medical illness, lack of social support and longer duration of... -
Helios + Regulatory T cell frequencies are correlated with control of viral r...
Abstract Background The acute phase of HIV infection is characterized by massive depletion of CD4 T cells, high viral plasma levels and pronounced systemic immune activation.... -
Transforming manufacturing to be ‘good for planet and people’, through enabli...
Abstract Background The United Nations’ Sustainable Development Goals remind us of the urgent need for every business to operate in ways that are good for planet and people.... -
Transcriptionally induced enhancers in the macrophage immune response to Myco...
Abstract Background Tuberculosis is a life-threatening infectious disease caused by Mycobacterium tuberculosis (M.tb). M.tb subverts host immune responses to build a favourable... -
Factors associated with health service orientation and active product marketi...
Abstract Background Little is known about pharmacy owners’ commitment to public health and health policy goals in the strategic planning of their business. The aim of this... -
Vasoresponsiveness in patients with heart failure (VASOR): protocol for a pro...
Abstract Background Vasoplegia is a severe complication which may occur after cardiac surgery, particularly in patients with heart failure. It is a result of activation of... -
The architecture of national boundary regimes: mapping immigration and citize...
Abstract In this article, I introduce a typology that maps the regulation of two fundamental boundaries of modern nation-states regarding immigration: territorial boundaries and... -
Prevalence, trend and contributing factors of geriatric syndromes among older...
Abstract Background Evidence is scarce on the trend in prevalence of geriatric syndromes (GS). This study assesses how GS prevalence changes over time in Swedish older... -
Contemporary women prisoners health experiences, unique prison health care ne...
Abstract Background Sub Saharan African (SSA) prisons have seen a substantial increase in women prisoners in recent years. Despite this increase, women prisoners constitute a... -
Trends in the epidemiology of young-onset colorectal cancer: a worldwide syst...
Abstract Background Recent data suggest that the risk of young-onset colorectal cancer (yCRC), in adults less than 50 years of age, is increasing. To confirm findings and... -
‘You are Okay’: a support and educational program for children with mild inte...
Abstract Background Children of parents with a mental illness or substance use disorder (COPMI) have an increased risk of developing social-emotional problems themselves. Fear... -
Pigmentary keratitis in pugs in the United Kingdom: prevalence and associated...
Abstract Background Pigmentary keratitis (PK) is commonly recognised in Pugs, but its aetiology is not completely understood. The aim of this study was to determine the... -
Effect of single follow-up home visit on readmission in a group of frail elde...
Abstract Background Unplanned hospital admissions are costly and prevention of these has been a focus for research for decades. With this study we aimed to determine whether... -
Copenhagen comorbidity in HIV infection (COCOMO) study: a study protocol for ...
Abstract Background Modern combination antiretroviral therapy (cART) has improved survival for people living with HIV (PLWHIV). Non-AIDS comorbidities have replaced... -
EWS and FUS bind a subset of transcribed genes encoding proteins enriched in ...
Abstract Background FUS (TLS) and EWS (EWSR1) belong to the FET-protein family of RNA and DNA binding proteins. FUS and EWS are structurally and functionally related and...