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Role of tyramine in calcium dynamics of GABAergic neurons and escape behavior...
Abstract Background Tyramine, known as a â trace amineâ in mammals, modulates a wide range of behavior in invertebrates; however, the underlying cellular and circuit... -
Building damage survey and microtremor measurements for the source region of ...
Abstract We performed a damage survey of buildings and carried out microtremor observations in the source region of the 2015 Gorkha earthquake. Our survey area spans the... -
Link of dysfunctional attitudes with the negative self-model
Abstract Background Beck’s cognitive theory postulates that dysfunctional attitudes predisposing to depression are formed by early negative experiences. Meanwhile, Bowlby’s... -
A qualitative study of carers’ experiences of dementia cafés: a place to feel...
Abstract Background Unpaid, informal carers or caregivers play an important role in supporting people living with dementia but the role can be challenging and carers themselves... -
Onset, timing, and exposure therapy of stress disorders: mechanistic insight ...
Abstract Background The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine system that regulates numerous physiological processes. Disruptions in the activity of the... -
Long-term prenatal exposure to paracetamol is associated with DNA methylation...
Abstract Background Epidemiological studies have shown that long-term exposure to paracetamol during pregnancy is associated with attention-deficit/hyperactivity disorder... -
Characteristics of functional enrichment and gene expression level of human p...
Abstract Background Transcriptional target genes show functional enrichment of genes. However, how many and how significantly transcriptional target genes include functional... -
Inflammatory pre-conditioning restricts the seeded induction of α-synuclein p...
Abstract Background Cell-to-cell transmission of α-synuclein (αSyn) is hypothesized to play an important role in disease progression in synucleinopathies. This process involves... -
Childhood traumatization is associated with differences in TRPA1 promoter met...
Abstract Background The construct of multisomatoform disorder (MSD) is a common point of reference for patients in different somatic and psychosomatic specialties and therefore... -
Risk factors for the development of acute respiratory distress syndrome in me...
Abstract Background Clinical and epidemiological differences between acute respiratory distress syndrome (ARDS) that presents at the initiation of mechanical ventilation [MV]... -
A CLCA regulatory protein present in the chemosensory cilia of olfactory sens...
Abstract Background CLCA is a family of metalloproteases that regulate Ca2+-activated Cl− fluxes in epithelial tissues. In HEK293 cells, CLCA1 promotes membrane expression of an... -
Neurally adjusted ventilatory assist versus pressure support ventilation: a r...
Abstract Background The clinical effectiveness of neurally adjusted ventilatory assist (NAVA) has yet to be demonstrated, and preliminary studies are required. The study aim was... -
Examining the role of spatial skills and mathematics motivation on middle sch...
Abstract Background Spatial skills and mathematical ability have been repeatedly identified as critical for achievement in Science, Technology, Engineering, and Mathematics... -
Upregulated 5-HT1A receptor-mediated currents in the prefrontal cortex layer ...
Abstract Serotonin (5-HT) is a well-known modulator of behavioral, physiological, and emotional functions of the forebrain region. We recently discovered alterations of... -
An investigation of the citation transformation types in M.A. and PhD theses
Abstract This study investigates the types of citation transformation preferred by both English L1 (native language) writers and Turkish writers who use English as a foreign... -
Passiflora incarnata attenuation of neuropathic allodynia and vulvodynia apro...
Abstract Background Passiflora incarnata is widely used as an anxiolytic and sedative due to its putative GABAergic properties. Passiflora incarnata L. methanolic extract... -
Involvement of brain-derived neurotrophic factor (BDNF) in chronic intermitte...
Abstract Background Reports show that stressful events before injury exacerbates post-injury pain. The mechanism underlying stress-induced heightened thermal pain is unclear.... -
Evaluation of apoptosis imaging biomarkers in a genetic model of cell death
Abstract Purpose We have previously developed the caspase-based radiotracer, 18F-ICMT-11, for PET imaging to monitor treatment response. We further validated 18F-ICMT-11... -
Kinetic analysis of [18F] altanserin bolus injection in the canine brain usin...
Abstract Background Currently, [18F] altanserin is the most frequently used PET-radioligand for serotonin2A (5-HT2A) receptor imaging in the human brain but has never been... -
The JAK-STAT Pathway Is Critical in Ventilator-Induced Diaphragm Dysfunction
Abstract Mechanical ventilation (MV) is one of the lynchpins of modern intensive-care medicine and is life saving in many critically ill patients. Continuous ventilator support,...