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Long-term prenatal exposure to paracetamol is associated with DNA methylation...
Abstract Background Epidemiological studies have shown that long-term exposure to paracetamol during pregnancy is associated with attention-deficit/hyperactivity disorder... -
Characteristics of functional enrichment and gene expression level of human p...
Abstract Background Transcriptional target genes show functional enrichment of genes. However, how many and how significantly transcriptional target genes include functional... -
Inflammatory pre-conditioning restricts the seeded induction of α-synuclein p...
Abstract Background Cell-to-cell transmission of α-synuclein (αSyn) is hypothesized to play an important role in disease progression in synucleinopathies. This process involves... -
Childhood traumatization is associated with differences in TRPA1 promoter met...
Abstract Background The construct of multisomatoform disorder (MSD) is a common point of reference for patients in different somatic and psychosomatic specialties and therefore... -
A CLCA regulatory protein present in the chemosensory cilia of olfactory sens...
Abstract Background CLCA is a family of metalloproteases that regulate Ca2+-activated Cl− fluxes in epithelial tissues. In HEK293 cells, CLCA1 promotes membrane expression of an... -
Upregulated 5-HT1A receptor-mediated currents in the prefrontal cortex layer ...
Abstract Serotonin (5-HT) is a well-known modulator of behavioral, physiological, and emotional functions of the forebrain region. We recently discovered alterations of... -
Passiflora incarnata attenuation of neuropathic allodynia and vulvodynia apro...
Abstract Background Passiflora incarnata is widely used as an anxiolytic and sedative due to its putative GABAergic properties. Passiflora incarnata L. methanolic extract... -
Involvement of brain-derived neurotrophic factor (BDNF) in chronic intermitte...
Abstract Background Reports show that stressful events before injury exacerbates post-injury pain. The mechanism underlying stress-induced heightened thermal pain is unclear.... -
A Nordic survey of CT doses in hybrid PET/CT and SPECT/CT examinations
Abstract Background Computed tomography (CT) scans are routinely performed in positron emission tomography (PET) and single photon emission computed tomography (SPECT)... -
Brain computerized tomography reading in suspected acute ischemic stroke pati...
Abstract Background Few systematic methods prioritize the image education in medical students (MS). We hope to develop a checklist of brain computerized tomography (CT) reading... -
Cryptic sequence features in the active postmortem transcriptome
Abstract Background Our previous study found that more than 500 transcripts significantly increased in abundance in the zebrafish and mouse several hours to days postmortem... -
Duox mediates ultraviolet injury-induced nociceptive sensitization in Drosoph...
Abstract Background Nociceptive sensitization is an increase in pain perception in response to stimulus. Following brief irradiation of Drosophila larvae with UV, nociceptive... -
Electroacupuncture at LI11 promotes jejunal motility via the parasympathetic ...
Abstract Background Gastrointestinal motility disorder has been demonstrated to be regulated by acupuncture treatment. The mechanisms underlying the effects of acupuncture... -
Potential risks in using midodrine for persistent hypotension after cardiac s...
Abstract Background Persistent hypotension is a frequent complication after cardiac surgery with cardiopulmonary bypass (CPB). Midodrine, an orally administered alpha agonist,... -
Genome-wide mapping of promoter-anchored interactions with close to single-en...
Abstract Although the locations of promoters and enhancers have been identified in several cell types, we still have limited information on their connectivity. We developed... -
Endo-lysosomal dysregulations and late-onset Alzheimer’s disease: impact of g...
Abstract Increasing evidence supports that cellular dysregulations in the degradative routes contribute to the initiation and progression of neurodegenerative diseases,...
