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Link of dysfunctional attitudes with the negative self-model
Abstract Background Beck’s cognitive theory postulates that dysfunctional attitudes predisposing to depression are formed by early negative experiences. Meanwhile, Bowlby’s... -
Onset, timing, and exposure therapy of stress disorders: mechanistic insight ...
Abstract Background The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine system that regulates numerous physiological processes. Disruptions in the activity of the... -
Long-term prenatal exposure to paracetamol is associated with DNA methylation...
Abstract Background Epidemiological studies have shown that long-term exposure to paracetamol during pregnancy is associated with attention-deficit/hyperactivity disorder... -
Characteristics of functional enrichment and gene expression level of human p...
Abstract Background Transcriptional target genes show functional enrichment of genes. However, how many and how significantly transcriptional target genes include functional... -
Childhood traumatization is associated with differences in TRPA1 promoter met...
Abstract Background The construct of multisomatoform disorder (MSD) is a common point of reference for patients in different somatic and psychosomatic specialties and therefore... -
A CLCA regulatory protein present in the chemosensory cilia of olfactory sens...
Abstract Background CLCA is a family of metalloproteases that regulate Ca2+-activated Cl− fluxes in epithelial tissues. In HEK293 cells, CLCA1 promotes membrane expression of an... -
Upregulated 5-HT1A receptor-mediated currents in the prefrontal cortex layer ...
Abstract Serotonin (5-HT) is a well-known modulator of behavioral, physiological, and emotional functions of the forebrain region. We recently discovered alterations of... -
Passiflora incarnata attenuation of neuropathic allodynia and vulvodynia apro...
Abstract Background Passiflora incarnata is widely used as an anxiolytic and sedative due to its putative GABAergic properties. Passiflora incarnata L. methanolic extract... -
Involvement of brain-derived neurotrophic factor (BDNF) in chronic intermitte...
Abstract Background Reports show that stressful events before injury exacerbates post-injury pain. The mechanism underlying stress-induced heightened thermal pain is unclear.... -
Evaluation of apoptosis imaging biomarkers in a genetic model of cell death
Abstract Purpose We have previously developed the caspase-based radiotracer, 18F-ICMT-11, for PET imaging to monitor treatment response. We further validated 18F-ICMT-11... -
Kinetic analysis of [18F] altanserin bolus injection in the canine brain usin...
Abstract Background Currently, [18F] altanserin is the most frequently used PET-radioligand for serotonin2A (5-HT2A) receptor imaging in the human brain but has never been... -
The JAK-STAT Pathway Is Critical in Ventilator-Induced Diaphragm Dysfunction
Abstract Mechanical ventilation (MV) is one of the lynchpins of modern intensive-care medicine and is life saving in many critically ill patients. Continuous ventilator support,... -
A Nordic survey of CT doses in hybrid PET/CT and SPECT/CT examinations
Abstract Background Computed tomography (CT) scans are routinely performed in positron emission tomography (PET) and single photon emission computed tomography (SPECT)... -
In silico modeling of phosphorylation dependent and independent c-Myc degrada...
Abstract Background c-Myc plays an important role in cell proliferation, cell growth and in differentiation, making it a key regulator for carcinogenesis and pluripotency. Tight... -
Does CRP predict outcome in bipolar disorder in regular outpatient care?
Abstract Background The association between inflammation and the course of mood disorders is receiving increased attention. This study aims to investigate whether a sub-group of... -
Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apopt...
Abstract Background A sustained inflammatory response following spinal cord injury (SCI) contributes to neuronal damage, inhibiting functional recovery. Macrophages, the major... -
Cryptic sequence features in the active postmortem transcriptome
Abstract Background Our previous study found that more than 500 transcripts significantly increased in abundance in the zebrafish and mouse several hours to days postmortem... -
Duox mediates ultraviolet injury-induced nociceptive sensitization in Drosoph...
Abstract Background Nociceptive sensitization is an increase in pain perception in response to stimulus. Following brief irradiation of Drosophila larvae with UV, nociceptive... -
Prone positioning in acute respiratory distress syndrome after abdominal surg...
Abstract Background The recent demonstration of prone position’s strong benefit on patient survival has rendered proning a major therapeutic intervention in severe ARDS.... -
Electroacupuncture at LI11 promotes jejunal motility via the parasympathetic ...
Abstract Background Gastrointestinal motility disorder has been demonstrated to be regulated by acupuncture treatment. The mechanisms underlying the effects of acupuncture...
