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Prolonged preoperative treatment of acromegaly with Somatostatin analogs may ...
Abstract Background This study aimed to investigate preoperative somatostatin analogs (SSAs) treatment on the surgical outcome in patients with acromegaly. Methods An analysis... -
Shifts in FGM/C practice in Sudan: communities’ perspectives and drivers
Abstract Background Although Sudan has one of the highest prevalence of female genital mutilation or cutting (FGM/C), there have been shifts in e practice. These shifts include... -
Neighbourhood fast food exposure and consumption: the mediating role of neigh...
Abstract Background The association between the residential fast food environment and diet has gained growing attention. However, why the food environment affects food... -
A Suspicion Index to aid screening of early-onset Niemann-Pick disease Type C...
Abstract Background Niemann-Pick disease Type C (NP-C) is difficult to diagnose due to heterogeneous and nonspecific clinical presentation. The NP-C Suspicion Index (SI) was... -
FNDC5 attenuates obesity-induced cardiac hypertrophy by inactivating JAK2/STA...
Abstract Background Chronic low-grade inflammation and oxidative stress play important roles in the development of obesity-induced cardiac hypertrophy. Here, we investigated the... -
Detection of critical cerebral desaturation thresholds by three regional oxim...
Abstract Background Regional oximetry is increasingly used to monitor post-extraction oxygen status of the brain during surgical procedures where hemodynamic fluctuations are... -
Oleogel-S10 Phase 3 study "EASE" for epidermolysis bullosa: study design and ...
Abstract Background Epidermolysis bullosa (EB) is a group of rare, genetic diseases that affect the integrity of epithelial tissues, most notably the skin. Patients experience... -
Leptin receptor signaling is required for high-fat diet-induced atrophic gast...
Abstract Background Obesity increases the risk for malignancies in various tissues including the stomach. Atrophic gastritis with precancerous lesions is an obesity-associated... -
Microglial depletion and repopulation in brain slice culture normalizes sensi...
Abstract Background Microglia are critical mediators of neuroimmune pathology across multiple neurologic disorders. Microglia can be persistently activated or “primed” by... -
Minimally Invasive Ponto Surgery compared to the linear incision technique wi...
Abstract Background Over the last years, less invasive surgical techniques with soft tissue preservation for bone conduction hearing implants (BCHI) have been introduced such as... -
Base excess and hematocrit predict response to indomethacin in very low birth...
Abstract Background The treatment of patent ductus arteriosus (PDA) in very low birth weight (VLBW) infants remains a challenge. The ability to predict which infants will... -
The effect of long working hours on 10-year risk of coronary heart disease an...
Abstract Background Recently, the emergence of long working hours and the associated conditions such as coronary heart disease (CHD) and stroke have gained attention. The aim of... -
Early BCG vaccine to low-birth-weight infants and the effects on growth in th...
Abstract Background Randomised trials have shown that early Bacille Calmette-Guérin (BCG) vaccine reduces overall neonatal and infant mortality. However, no study has examined...
