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Glucocorticoids promote transition of ductal carcinoma in situ to invasive du...
Abstract Background The microenvironment and stress factors like glucocorticoids have a strong influence on breast cancer progression but their role in the first stages of... -
Synthetic control devices for gene regulation in Penicillium chrysogenum
Abstract Background Orthogonal, synthetic control devices were developed for Penicillium chrysogenum, a model filamentous fungus and industrially relevant cell factory. In the... -
In situ virtual restoration of artifacts by imaging technology
Abstract The restoration of incomplete artifacts is important for presenting the value of artifacts. Even though the existing methods provide rich solutions for the restoration... -
Transcriptome analysis reveals regional and temporal differences in mucosal i...
Abstract Background Postnatal development of the mammalian mucosal immune system is crucial for responding to the rapid colonization by commensal bacteria and possible exposure... -
Netrin-1 attenuates brain injury after middle cerebral artery occlusion via d...
Abstract Background Netrin-1 functions largely via combined receptors and downstream effectors. Evidence has shown that astrocytes express netrin-1 receptors, including DCC and... -
High shear stress suppresses proliferation and migration but promotes apoptos...
Abstract Background Early neointimal hyperplasia of vein graft may be ameliorated via enhancing intravenous surface shear stress. Cellular processes including proliferation,... -
Postural effects on intraocular pressure and ocular perfusion pressure in pat...
Abstract Background To investigate postural effects on intraocular pressure (IOP) and ocular perfusion pressure (OPP) in patients with non-arteritic ischemic optic neuropathy... -
Simultaneous single-shot real-time measurement of the instantaneous frequency...
A self-reference, single-shot characterization technique is proposed and demonstrated for simultaneously measuring the instantaneous frequencies and phases of multi-wavelength... -
Implementing a bedside assessment of respiratory mechanics in patients with a...
Abstract Background Despite their potential interest for clinical management, measurements of respiratory mechanics in patients with acute respiratory distress syndrome (ARDS)... -
Severe burn injury alters intestinal microbiota composition and impairs intes...
Abstract Background The intestinal barrier integrity is crucial for maintaining intestinal homeostasis, and the mechanisms of intestinal barrier disruption induced by burn... -
Rough surface Au@Ag core–shell nanoparticles to fabricating high sensitivity ...
Abstract Immunochromatographic sensors (ICSs) are inexpensive, simple, portable, and robust, thus making ICSs commonplace in clinical diagnoses, food testing, and environmental... -
Is Bulpa criteria suitable for the diagnosis of probable invasive pulmonary A...
Abstract Background Three diagnostic criteria have been proposed used for invasive pulmonary aspergillosis (IPA) diagnosis, namely EORTC/ MSG criteria, Bulpa criteria and... -
Preclinical in vivo application of 152Tb-DOTANOC: a radiolanthanide for PET i...
Abstract Background Terbium has attracted the attention of researchers and physicians due to the existence of four medically interesting radionuclides, potentially useful for... -
The Effect of Everolimus on Scar Formation in Glaucoma Filtering Surgery in a...
Purpose: To investigate the efficiency of everolimus on the prevention of postoperative scar in a rabbit model of glaucoma filtering surgery in comparison with mitomycin-C... -
Interference between surgical magnetic drapes and pacemakers: an observationa...
Abstract Background Magnetic fields may potentially interfere with the function of cardiovascular implantable electronic devices. Sterile magnetic drapes used to hold surgical... -
Effect of boundary on refractive index of PDMS
In this contribution we present some results of a study of a refractive index inhomogeneity near the boundary of polydimethylsiloxane (PDMS) samples. We have observed... -
Interactive application in holographic optical tweezers of a multi-plane Gerc...
Phase-hologram patterns that can shape the intensity distribution of a light beam in several planes simultaneously can be calculated with an iterative Gerchberg-Saxton algorithm... -
Development of drug-inducible CRISPR-Cas9 systems for large-scale functional ...
Abstract Background Large-scale genetic screening using CRISPR-Cas9 technology has emerged as a powerful approach to uncover and validate gene functions. The ability to control... -
Overexpression of MALT1-A20-NF-κB in adult B-cell acute lymphoblastic leukemia
Abstract Background A20 is a dual inhibitor of NF-κB activation and apoptosis in the tumor necrosis factor receptor 1 signaling pathway, and both are related to tumorigenesis.... -
Kinetic, kinematic, magnetic resonance and owner evaluation of dogs before an...
Abstract Background The amputation of a limb is a surgical procedure that is regularly performed in small animal practice. In spite of several clinical reports indicating high...