-
VEGF-121 plasma level as biomarker for response to anti-angiogenetic therapy ...
Abstract Background Vascular endothelial growth factor (VEGF) isoforms, particularly the diffusible VEGF-121, could play a major role in the response of recurrent glioblastoma... -
Effects of endogenous sex hormones on lung function and symptom control in ad...
Abstract Background Although pre-puberty asthma is more prevalent in males, after puberty through middle-age, asthma is more prevalent in females. The surge of sex hormones with... -
Comparison of the source and prognostic utility of cfDNA in trauma and sepsis
Abstract Background Circulating cell-free DNA (cfDNA) may contribute to the pathophysiology of post-injury inflammation and coagulation in trauma. However, the source and... -
Male involvement in the maternal health care system: implication towards decr...
Abstract Background One of the essential components of antenatal care (ANC) is birth preparedness and complication readiness (BP/CR). Strengthening BP/CR measures is one of the... -
C-reactive protein mediates the association between leisure-time physical act...
Abstract Background Although previous studies have reported the benefits of physical activity (PA) to lung function in middle-aged and older adults, the biological mechanisms... -
Impact of malnutrition on systemic immune and metabolic profiles in type 2 di...
Abstract Background While obesity and overweight status are firmly established risk factors for Type 2 diabetes mellitus (T2DM), a substantial proportion of diabetic... -
Evaluation of the association of Wnt signaling with coronary artery calcifica...
Abstract Background Patients with end-stage renal disease have a higher risk of death from cardiovascular events, which can be mainly attributed to coronary artery calcification... -
Adverse drug reactions in older adults: a retrospective comparative analysis ...
Abstract Background Older adults are more prone to develop adverse drug reactions (ADRs) since they exhibit numerous risk factors. The first aim was to analyse the number of... -
Hematoma block or procedural sedation and analgesia, which is the most effect...
Abstract Background Procedure sedation and analgesia (PSA) is often used to alleviate discomfort and to facilitate fracture reduction for patients with distal radius fracture in... -
Waist circumference is associated with major adverse cardiovascular events in...
Abstract Background Although studies have shown that waist circumference (WC) is positively associated with an increased risk of cardiovascular diseases among the normal... -
Serious infections in patients with self-reported psoriatic arthritis from th...
Abstract Background Patients with psoriatic arthritis (PsA) have increased risk of adverse events, including serious infections (SI), compared with psoriasis patients. Methods... -
Regulatory single nucleotide polymorphisms (rSNPs) at the promoters 1A and 1B...
Abstract Background Germline mutations in the coding sequence of the tumour suppressor APC gene give rise to familial adenomatous polyposis (which leads to colorectal cancer)... -
Development of a cardiac-centered frailty ontology
Abstract Background A Cardiac-centered Frailty Ontology can be an important foundation for using NLP to assess patient frailty. Frailty is an important consideration when making... -
"Yellow-dragon Wonderful-seed Formula" for hyperuricemia in gout patients wit...
Abstract Background In Traditional Chinese Medicine (TCM) theories, the typical clinical manifestations of gout are attributed to the “dampness-heat pouring downward.”... -
Self-illuminating quantum dots for non-invasive bioluminescence imaging of ma...
Abstract Background The fertility performance of animals is still a mystery and the full comprehension of mammalian gametes maturation and early embryonic development remains to... -
Do antibacterial skin sutures reduce surgical site infections after elective ...
Abstract Background Surgical site infections (SSI) remain one of the most common complications in conventional abdominal surgery with an incidence between 4% and 19% (Sandini et... -
Development and evaluation of adsorption sheet (HD safe sheet-U) using active...
Abstract Background Certain amount of anticancer drugs is excreted in the urine of patients receiving anticancer drugs, and urinary scattering including anticancer drugs at... -
Intravenous ivabradine versus placebo in patients with low cardiac output syn...
Abstract Background Low cardiac output syndrome (LCOS) is a severe condition which can occur after cardiac surgery, especially among patients with pre-existing left ventricular... -
Uterine Tonus Assessment by Midwives versus Patient self-assessment in the ac...
Abstract Background Postpartum hemorrhage (PPH) is the leading cause of maternal mortality worldwide and accounts for one third of maternal deaths in low-income and... -
Gabapentin as add-on to morphine for severe neuropathic or mixed pain in chil...
Abstract Background Gabapentin has shown efficacy in the treatment of chronic neuropathic or mixed pain in adults. Although pediatric pain specialists have extensive experience...
