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The validity of pediatric cancer diagnoses in a population-based general canc...
Abstract Background Data from population-based cancer registries are increasingly used to conduct research and guide policy. However, few validation studies of cancer registry... -
Resveratrol mediates mechanical allodynia through modulating inflammatory res...
Abstract Background Neuropathic pain (NeuP) is a chronic and challenging clinical problem, with little effective treatment. Resveratrol has shown neuroprotection by inhibiting... -
Modelling population-level impact to inform target product profiles for child...
Abstract Background The RTS,S/AS01 vaccine for Plasmodium falciparum malaria demonstrated moderate efficacy in 5â 17-month-old children in phase 3 trials, and from 2018, the... -
Morbidity burden of respiratory diseases attributable to ambient temperature:...
Abstract Background There are significant associations between ambient temperature and respiratory disease mortality. However, few studies have assessed the morbidity burdens of... -
Critique of a practice-based pilot study in chiropractic practices in Western...
Abstract Background Practice-based data collection can offer insight into the nature of chiropractic practice and contribute to resolving the conundrum of the chiropractic... -
Serum levels of B-cell activating factor of the TNF family (BAFF) correlate w...
Abstract Background B-cell activating factor of the tumour necrosis factor family (BAFF) plays a role in autoantibody production and is elevated in dermatomyositis (DM) and... -
Low levels of pyruvate induced by a positive feedback loop protects cholangio...
Abstract Background Cancer cells avidly consume glucose and convert it to lactate, resulting in a low pyruvate level. This phenomenon is known as the Warburg effect, and is... -
Erectile dysfunction and associated factors among men with diabetes mellitus ...
Abstract Objective Prevalence of erectile dysfunction (ED) in diabetic men is considerably high but it is often underdiagnosed and undermanaged. There were no data available... -
Factors influencing the time between onset of illness and specimen collection...
Abstract Background Listeriosis is an opportunistic bacterial infection caused by Listeria monocytogenes and predominantly affects people who are immunocompromised. Due to its... -
Burden of non-communicable diseases among Syrian refugees: a scoping review
Abstract Background The scarcity of evidence-based research on non-communicable diseases (NCDs) among Syrian refugees has hampered efforts to address the high burden of these... -
Comparative utility of frailty to a general prognostic score in identifying p...
Abstract Background Current guidelines recommend considering life expectancy before aortic valve replacement (AVR). We compared the performance of a general mortality index, the... -
Association between component-resolved diagnosis of house dust mite and effic...
Abstract Data regarding clinical relevance of house dust mite (HDM) components over allergen immunotherapy (AIT) for allergic rhinitis (AR) are lacking. 18 adult AR patients... -
Association between objectively measured physical activity and body mass inde...
Abstract Background The relationship between the combination of physical activity (PA) and body mass index (BMI) with low back pain (LBP) is unclear. The present study offers a... -
Possible beneficial association between renin-angiotensin-aldosterone-system ...
Abstract Background Although immunoglobulin A nephropathy (IgAN) is associated with an increased risk of renal allograft failure, evidences for its treatment, including... -
The impact of disease severity on paradoxical association between body mass i...
Abstract Background Association between high body mass index (BMI) and survival benefit is confounded by comorbid conditions such as nutritional status and inflammation.... -
Amorphous silica nanoparticles induce malignant transformation and tumorigene...
Rapid development and deployment of engineered nanomaterials, such as amorphous silica nanoparticles (SiNPs) in various commercial and biomedical applications have raised... -
Concomitant NSAID use during antipsychotic treatment and risk of 2-year relap...
Objective: Clinical trials have indicated antipsychotic effects of non-steroidal anti-inflammatory drugs (NSAIDs) among incident patients with schizophrenia. We aimed to study,... -
ATLANTIS: a randomised multi-arm phase II biomarker-directed umbrella screeni...
Abstract Background Metastatic urothelial cancer (UC) is the eighth most common cause of cancer death in the UK. Standard first-line treatment, for most patients, is cytotoxic... -
Relationship between viral dose and outcome of infection in Atlantic salmon, ...
Abstract Salmonid alphavirus subtype 3 (SAV3) causes pancreas disease (PD) and adversely affects salmonid aquaculture in Europe. A better understanding of disease transmission... -
Assessing the impact of the Barbados sugar-sweetened beverage tax on beverage...
Abstract Background The World Health Organization has advocated for sugar-sweetened beverage (SSB) taxes as part of a broader non-communicable disease prevention strategy, and...