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Checklist to operationalize measurement characteristics of patient-reported o...
Abstract Background The purpose of this study was to advance a checklist of evaluative criteria designed to assess patient-reported outcome (PRO) measuresâ developmental... -
An ethanol extract of <i>Ramulus mori</i> improves blood circulation by inhib...
Inappropriate platelet aggregation can cause blood coagulation and thrombosis. In this study, the effect of an ethanol extract of Ramulus mori (ERM) on blood circulation was... -
Clinical baseline and prognostic difference of platelet lymphocyte ratio (PLR...
Abstract Background Right-sided colon cancer (RCC) and left-sided colon cancer (LCC) differ with respect to their biology and genomic patterns, but inflammatory index variation... -
Factor structure and internal reliability of cultural belief scales about col...
Abstract Background Culturally sensitive, reliable and valid cultural belief scales for colorectal cancer (CRC) screening in Koreans in the Republic of Korea are not available... -
Mutational spectrum of acquired resistance to reversible versus irreversible ...
Abstract Background Over the past years, EGFR tyrosine kinase inhibitors (TKI) revolutionized treatment response. 1st-generation (reversible) EGFR TKI and later the 2nd... -
Ultrahigh speed Spectral / Fourier domain OCT ophthalmic imaging at 70,000 to...
We demonstrate ultrahigh speed spectral/Fourier domain optical coherence tomography (OCT) using an ultrahigh speed CMOS line scan camera at rates of 70,000–312,500 axial scans... -
The Brazillian version of the hand mobility in scleroderma (HAMIS) test: tran...
Abstract Background The Hand Mobility in Scleroderma (HAMIS) test was created to measure the degree of dysfunction of hand movements imposed by systemic sclerosis (SSc). The... -
High-speed terahertz reflection three-dimensional imaging using beam steering
High-speed terahertz (THz) reflection three-dimensional (3D) imaging is demonstrated using electronically-controlled optical sampling (ECOPS) and beam steering. ECOPS... -
Mesenchymal stem cell-derived exosomes improve motor function and attenuate n...
Abstract Background Machado-Joseph disease is the most common autosomal dominant hereditary ataxia worldwide without effective treatment. Mesenchymal stem cells (MSCs) could... -
Treatment outcomes of drug-resistant tuberculosis in the Netherlands, 2005–2015
Abstract Background Since in low incidence TB countries population migration and complex treatment of drug-resistant tuberculosis (DR-TB) patients are major issues, we aimed to... -
Non-invasive detection of endometrial cancer by DNA methylation analysis in u...
Abstract Background The incidence of endometrial cancer is rising, and current diagnostics often require invasive biopsy procedures. Urine may offer an alternative sample type,... -
Translation and validation of two disease-specific patient-reported outcome m...
Abstract Background The Bladder Cancer Index (BCI) and Functional Assessment of Cancer Therapy-Bladder-Cystectomy (FACT-Bl-Cys) were developed to measure disease-specific... -
GMP-grade neural progenitor derivation and differentiation from clinical-grad...
Abstract Background A major challenge for the clinical use of human pluripotent stem cells is the development of safe, robust and controlled differentiation protocols.... -
An ovarian bioreactor for in vitro culture of the whole bovine ovary: a preli...
Abstract Background Improved cancer therapeutics and enhanced cancer survivorship have emphasized the severe long-term side effects of chemotherapy. Specifically, studies have... -
The repeatability of superficial retinal vessel density measurements in eyes ...
Abstract Background To investigate the repeatability of superficial retinal vessel density measurements in healthy eyes with long axial length (AL) using optical coherence... -
Frequent hypermethylation of orphan CpG islands with enhancer activity in cancer
Abstract Background CpG islands (CGIs) are interspersed DNA sequences that have unusually high CpG ratios and GC contents. CGIs are typically located in the promoter of... -
Reference markers of bone turnover for prediction of fracture: a meta-analysis
Abstract Objective To explore whether bone turnover biomarkers (BTMs), i.e., C-terminal telopeptide of type I collagen (CTX) and procollagen type I aminoterminal propeptide...