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Ablation of epidermal RXRα in cooperation with activated CDK4 and oncogenic N...
Abstract Background Understanding the underlying molecular mechanisms involved in the formation of cutaneous malignant melanoma is critical for improved diagnosis and treatment.... -
A novel transcription factor specifically regulates GH11 xylanase genes in Tr...
Abstract Background The filamentous fungus Trichoderma reesei is widely utilized in industry for cellulase production, but its xylanase activity must be improved to enhance the... -
General practitioners’ continuation and acceptance of medication changes at s...
Abstract Background Follow-up in general practice on medication initiated during hospitalisation is often perceived to be inadequate, which leads to unintended drug interaction... -
Accelerating newborn survival in Ghana through a low-dose, high-frequency hea...
Abstract Background Newborn deaths comprise nearly half of under-5 deaths in Ghana, despite the fact that skilled birth attendants (SBAs) are present at 68% of births, which... -
How effective are digital interventions in increasing flu vaccination amongst...
Abstract Background Pregnant women and their unborn babies are at increased risk of complications as a result of flu, yet uptake of the flu vaccination in the UK remains low.... -
Sublingual microcirculation does not reflect red blood cell transfusion thres...
Abstract Purpose Hemoglobin (Hb) transfusion thresholds are established in intensive care units. A restrictive transfusion threshold (Hb 70–75 g/l) is recommended in septic... -
Nutritional situation among Syrian refugees hosted in Iraq, Jordan, and Leban...
Abstract Background Ongoing armed conflict in Syria has caused large scale displacement. Approximately half of the population of Syria have been displaced including the millions... -
Mechanisms and direction of allocation bias in randomised clinical trials
Abstract Background Selective allocation of patients into the compared groups of a randomised trial may cause allocation bias, but the mechanisms behind the bias and its... -
Development of an infant feeding core outcome set for childhood obesity inter...
Abstract Background Childhood obesity is a significant public health challenge that affects approximately one in five children worldwide. Infant feeding practices are implicated... -
Risk factors for death among children 0–59 months of age with moderate-to-sev...
Abstract Background Despite major improvements in child survival rates, the number of deaths due to diarrhea remains unacceptably high. We aimed to describe diarrhea-associated... -
Biotransformation of keratin waste to amino acids and active peptides based o...
Abstract Background Keratin is the primary constituent of the vertebrate epidermis and epidermal appendages, as well as the main waste product generated during poultry... -
Epidermal grafting versus split-thickness skin grafting for wound healing (EP...
Abstract Background Split-thickness skin grafting (SSG) is an important modality for wound closure. However, the donor site becomes a second, often painful wound, which may take... -
Factors influencing the practice of exclusive breastfeeding among nursing mot...
Abstract Background Exclusive breastfeeding (EBF) is one of the optimal infant and young child feeding practices. Globally, <40% of infants under 6 months of age are... -
Development of a Core Outcome Set for Studies on Obesity in Pregnant Patients...
Abstract Background Maternal obesity is a risk factor for adverse maternal, fetal, and neonatal events. Numerous clinical trials are currently exploring the effectiveness of... -
Hemodynamic impacts of flow diverter devices on the ophthalmic artery
Abstract Background Flow diverter devices are increasingly used for endovascular treatment of internal carotid artery aneurysms. Treatment of ophthalmic segment aneurysms with... -
The effect of the Xpert MTB/RIF test on the time to MDR-TB treatment initiati...
Abstract Background There are significant delays in initiation of multidrug-resistant tuberculosis (MDR –TB) treatment. The Xpert MTB/RIF test has been shown to reduce the time... -
Consensus of potential modifiable prognostic factors for persistent pain afte...
Abstract Background Identify and establish consensus regarding potential prognostic factors for the development of chronic pain after a first episode of idiopathic,... -
Initial nutritional management during noninvasive ventilation and outcomes: a...
Abstract Background Patients starting noninvasive ventilation (NIV) to treat acute respiratory failure are often unable to eat and therefore remain in the fasting state or... -
Training and well-equipped facility increases the odds of skills of health pr...
Abstract Background Health professionals equipped with the adequate skills of helping baby breath remain the backbone in the health system in improving neonatal outcomes.... -
Prescription drug use and potential teratogenicity risk among pregnant women ...
Abstract Objective To investigate medications prescribed for pregnant women and their potential teratogenicity risk in Kemisse General Hospital. Result A total of 263 medical...
