-
A p53/TIAF1/WWOX triad exerts cancer suppression but may cause brain protein ...
Abstract Background Tumor suppressor WWOX physically binds p53 and TIAF1 and together induces apoptosis and tumor suppression. To understand the molecular action, here we... -
Waist height ratio predicts chronic kidney disease: a systematic review and m...
Abstract Background The incidence of chronic kidney disease (CKD) increases each year, and obesity is an important risk factor for CKD. The main anthropometric indicators... -
Characteristics and impact of the most-cited palliative oncology studies from...
Abstract Background Palliative care, as a relatively young field within medicine, has increasingly used original research to validate and standardize its practice. In... -
Do disciplinary contexts impact the learning of evolution? Assessing knowledg...
Abstract Background Evolution education research has focused on biology populations, while other disciplines organized around evolutionary theory—such as biological... -
Interventions to improve discharge from acute adult mental health inpatient c...
Abstract Background The transition from acute mental health inpatient to community care is often a vulnerable period in the pathway, where people can experience additional risks... -
The impact of diabetes on multiple avoidable admissions: a cross-sectional study
Abstract Background Multiple admissions for ambulatory care sensitive conditions (ACSC) are responsible for an important proportion of health care expenditures. Diabetes is one... -
Patient-reported outcome measures: selection of a valid questionnaire for rou...
Abstract Background Patient-reported outcome measures (PROMs) are becoming increasingly important in healthcare. In nephrology, there is no agreement on which chronic kidney... -
The patient reporting and action for a safe environment (PRASE) intervention:...
Abstract Background There is growing interest in the role of patients in improving patient safety. One such role is providing feedback on the safety of their care. Here we... -
The early childhood oral health program: a qualitative study of the perceptio...
Abstract Background Early childhood caries affects nearly half the population of Australian children aged 5Â years and has the potential to negatively impact their growth and... -
Ultrahigh speed 1050nm swept source / Fourier domain OCT retinal and anterior...
We demonstrate ultrahigh speed swept source/Fourier domain ophthalmic OCT imaging using a short cavity swept laser at 100,000 – 400,000 axial scan rates. Several design... -
Synthesizing existing evidence to design future trials: survey of methodologi...
Abstract Background â Conditional trial designâ is a framework for efficiently planning new clinical trials based on a network of relevant existing trials. The framework... -
Validation of genotype cluster investigations for Mycobacterium tuberculosis:...
Abstract Background Tracking the dissemination of specific Mycobacterium tuberculosis (Mtb) strains using genotyped Mtb isolates from tuberculosis patients is a routine public... -
Clinical performance of decellularized heart valves versus standard tissue co...
Abstract Background Valve replacement surgery is the definitive management strategy for patients with severe valvular disease. However, valvular conduits currently in clinical... -
Circadian disruption of core body temperature in trauma patients: a single-ce...
Abstract Background Circadian clock alterations were poorly reported in trauma patients, although they have a critical role in human physiology. Core body temperature is a... -
Gender-based generalisations in school nurses’ appraisals of and intervention...
Abstract Background There has been an increase of reports describing mental health problems in adolescents, especially girls. School nurses play an important role in supporting... -
Recruiting to Clinical Trials on the Telephone – a randomized controlled trial
Abstract Background Informed consent is an essential element of clinical research. Obtaining consent, however, may be challenging. The use of the telephone for giving... -
Similarities and differences between stakeholders’ opinions on using Health T...
Abstract Background The European-study on Quantifying Utility of Investment in Protection from Tobacco (EQUIPT) project aimed to study transferability of economic evidence by... -
Individualised behaviour change strategies for physical activity in multiple ...
Abstract Background Multiple sclerosis (MS) is a chronic, degenerative disease of the central nervous system. Because of the long-term and unpredictable nature of the disease,... -
The burden of laboratory-confirmed pertussis in low- and middle-income countr...
Abstract Background An effective vaccine against Bordetella pertussis was introduced into the Expanded Programme on Immunisation (EPI) by WHO in 1974, leading to a substantial... -
Translation, cross-cultural adaptation and reliability of the German version ...
Abstract Background The Migraine Disability Assessment (MIDAS) is a brief questionnaire and measures headache-related disability. This study aimed to translate and...
