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"Yellow-dragon Wonderful-seed Formula" for hyperuricemia in gout patients wit...
Background In Traditional Chinese Medicine (TCM) theories, the typical clinical manifestations of gout are attributed to the “dampness-heat pouring downward.” Therefore, TCM... -
Objective coding of content and techniques in workplace-based supervision of ...
Background Workplace-based clinical supervision as an implementation strategy to support evidence-based treatment (EBT) in public mental health has received limited research... -
Quality of pilot trial abstracts in heart failure is suboptimal: a systematic...
Background Pilot trials are miniature researches carried out with the sole aim of acting as the precursor for larger more definitive studies. Abstracts are used to summarize and... -
Alcohol misuse and outpatient follow-up after hospital discharge: a retrospec...
Purpose Patients with alcohol misuse are less likely to receive preventive health services but more likely to utilize emergency health services. However, the association between... -
Access criteria for anti-TNF agents in spondyloarthritis: influence on compar...
Background: Anti-tumor necrosis factor (anti-TNF) agents are an effective, but costly, treatment for spondyloarthritis (SpA). Worldwide, multiple sets of access... -
Professional fulfillment and parenting work-life balance in female physicians...
Background In Japan, the field of Basic Sciences encompasses clinical, academic, and translational research, as well as the teaching of medical sciences, with both an MD and PhD... -
T-CaST: an implementation theory comparison and selection tool
Background Theories, models, and frameworks (TMF) are foundational for generalizing implementation efforts and research findings. However, TMF and the criteria used to select... -
Understanding HRH recruitment in post-conflict settings: an analysis of centr...
Background Although human resources for health (HRH) represent a critical element for health systems, many countries still face acute HRH challenges. These challenges are... -
Hospital recruitment for a pragmatic cluster-randomized clinical trial: Lesso...
Background Pragmatic randomized clinical trials are essential to determine the effectiveness of interventions in “real-world” clinical practice. These trials frequently use a... -
Women’s views and experiences of two alternative consent pathways for partici...
Background The Cord Pilot Trial compared alternative policies for timing of cord clamping at very preterm birth at eight UK hospitals. In addition to standard written consent,... -
Learning from OCTET – exploring the acceptability of clinical trials manageme...
Background Conducting research can be time consuming, difficult and challenging. Guidance and pragmatic advice focussing on randomised controlled trial conduct are available but... -
BADERI: an online database to coordinate handsearching activities of controll...
Background Systematic reviews provide the best evidence on the effect of health care interventions. They rely on comprehensive access to the available scientific literature.... -
Adaptation of the Ambulatory and Home Care Record for collecting palliative c...
Background Measuring service use and costs is an important aspect of service delivery evaluation. In end-of-life care, there is heavy reliance on care by family/friends... -
Targeting ectodysplasin promotor by CRISPR/dCas9-effector effectively induces...
Background Patients with a deep burn injury are characterized by losing the function of perspiration and being unable to regenerate the sweat glands. Because of their easy... -
A pivotal role of BEX1 in liver progenitor cell expansion in mice
Background The activation and expansion of bipotent liver progenitor cells (LPCs) are indispensable for liver regeneration after severe or chronic liver injury. However, the... -
A description of health care system factors in the implementation of universa...
Background The prevalence of childhood obesity poses an urgent global challenge. The World Health Organization (WHO) Commission on Ending Childhood Obesity recommends the... -
Enhancing the uptake of systematic reviews of effects: what is the best forma...
Background Systematic reviews are infrequently used by health care managers (HCMs) and policy-makers (PMs) in decision-making. HCMs and PMs co-developed and tested novel... -
Data for Improvement and Clinical Excellence: a report of an interrupted time...
Background There is substantial evidence about the effectiveness of audit with feedback, but none that we know have been conducted in home care settings. The primary purpose of... -
BCN057 induces intestinal stem cell repair and mitigates radiation-induced in...
Background Radiation-induced gastrointestinal syndrome (RIGS) results from the acute loss of intestinal stem cells (ISC), impaired epithelial regeneration, and subsequent loss... -
A feasibility randomised controlled trial of extended brief intervention for ...
Background Extended brief interventions (EBIs) are effective in targeting alcohol misuse in the general population. However, little is known of the effects of EBI in adults with...
