4 items found

Licenses: License Not Specified Tags: Genomics keywords.Structural Biology

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  • publication

    NEAT: a framework for building fully automated NGS pipelines and analyses

    Background: The analysis of next generation sequencing (NGS) has become a standard task for many laboratories in the life sciences. Though there exists several tools to support...
  • publication

    SCNS: a graphical tool for reconstructing executable regulatory networks from...

    Background Reconstruction of executable mechanistic models from single-cell gene expression data represents a powerful approach to understanding developmental and disease...
  • publication

    Updated and standardized genome-scale reconstruction of <i>Mycobacterium tube...

    Background The efficacy of antibiotics against M. tuberculosis has been shown to be influenced by experimental media conditions. Investigations of M. tuberculosis growth in...
  • publication

    Viral diversity is an obligate consideration in CRISPR/Cas9 designs for targe...

    Background RNA-guided CRISPR/Cas9 systems can be designed to mutate or excise the integrated HIV genome from latently infected cells and have therefore been proposed as a...