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r37980778c78--d0850284f6e377c80587f5ff34b89303
A, B, Quantitative RT-PCR result of IDE in TR-AST cells and rat primary astrocytes. TR-AST cells and primary astrocytes were treated with hydrogen peroxide in indicated... -
Demographics and clinical characteristics.
Values are mean ± standard deviation unless otherwise noted. Categorical data are compared by chi-square tests, two tailed; all other p values are by Student's t test, two tailed. -
r37980778c78--63549404e57ce98cbeaf0acd9647a040
As Alzheimer’s disease (AD) induces several cellular and molecular damages, it could be interesting to use multi-target molecules for therapeutics. We previously published that... -
r37980778c78--72863fa0d97e1fa06d473e90665dbc5b
A, Each circle is indicating the numbers of either up or down regulated genes by oxidative stress, aging in the cerebrum and in the cerebellum. Five genes were up-regulated and... -
Meta-analyses of comparative efficacy of antidepressant medications on periph...
BackgroundBrain derived neurotrophic factor (BDNF) is one of the most important regulatory proteins in the pathophysiology of major depressive disorder (MDD). Increasing numbers... -
Induction of Pla2g3 expression in cerebrum by oxidative stress.
A, B, Quantitative RT-PCR results of Pla2g3 in cerebrum and cerebellum are shown. Fold changes to the aged wild-type mice on normal diet are indicated. n = 4 in each group. C,... -
r37980778c78--cdbf842081c565e3241ca47b0e32a752
Oxidative stress has a ubiquitous role in neurodegenerative diseases and oxidative damage in specific regions of the brain is associated with selective neurodegeneration. We... -
r37980778c78--c9dc95d4a38a42d25cc5cbe259123473
A, Pla2g3 expression in normal control brain and AD brain. The images are representative of 6 cases in each group. Frontal cortex was stained with anti-Pla2g3 antibody. B,... -
Cognitive assessments and concentrations of plasma t-tau in patients with DS.
Cognitive assessments and concentrations of plasma t-tau in patients with DS. -
Summary of Results.
Summary of results of follicle number counts, mRNA analyses and oxidative stress measures in ovaries of offspring born to mothers undernourished during pregnancy (UNP), during... -
Participant Demographics.
1Age at enrolment,2mean value (range),3Body Mass Index,4Pre-enrolment IgA anti-tissue transglutaminase (normal range below 20 U/ml),5duration of... -
Baseline characteristics of the study population.
Values are expressed as medians (range or percentage). * Hypertension: Yes = systolic blood pressure ≥140 mmHg, diastolic blood pressure ≥90 mmHg, or treated with... -
Experimental groups.
Adult male and female mice used in this study were; Mc1re, recessive yellow mice, which are null mutants with a non-functional MC1R resulting in a yellow coat colour and their... -
Cohort characteristics.
BMI, body mass index; IBD, inflammatory bowel disease; CD: Crohn's disease; UC: Ulcerative colitis. P25, P75: 25th and 75th percentiles; SD: standard deviation. *p<0.05 versus... -
Characteristics of Study Subjects at Baseline.
NOTE. Values are expressed as mean ± standard deviation. No significant differences in clinical variables were found between TRC and Placebo group at baseline, p<0.05. The body... -
Network Analysis of a Comprehensive Knowledge Repository Reveals a Dual Role ...
Alzheimer’s disease (AD) is the most common cause of senile dementia. Many inflammatory factors such as amyloid-β and pro-inflammatory cytokines are known to contribute to the... -
Classification results
This table contrasts the classification results obtained through generative embedding with those afforded by three conventional methods. As described in the main text, the... -
Summary statistics.
Values are presented as Mean ±SEM. Abbreviations: fWHR [34]; EME [44]; ULh, LLh and Nw [33]; Index 1 [47], Index 2 [48], [50], Index 3 [10], [49], ProcDist [54], [79], DiscSco1...
