-
r37980778c78--56fcee8741a21a8729fa2db393bd30b0
Design, synthesis, and in vitro bioevaluation of a new class of potential dual PPARα and γ agonists discovered through a structure-driven design paradigm are described. The... -
System boundary selection in life-cycle inventories using hybrid approaches
Life-cycle assessment (LCA) is a method for evaluating the environmental impacts of products holistically, including direct and supply chain impacts. The current LCA... -
Access Control
Publisher Summary Access control is the control of access to property, services, events, or information, and is a combination of several things including control, record... -
r37980778c78--fe4e83e064bdf00dc834ea490c40288c
A ratiometric fluorescent biosensor for Hg2+ is constructed from the MerR protein and a duplex DNA containing a pyrene excimer. -
Inherently Chiral Biscalix[4]arenes: Design and Syntheses
Inherently chiral biscalix[4]arenes have been designed and synthesized by covalently assembling two calix[4]arene building blocks in a 1,3-position linking with 1,2-position... -
r37980778c78--566516baee56754d67c275c2225a172b
We previously prepared the oligonucleotides (ODNs) conjugated to an anthraquinone (AQ) group via one carbon linker at the 2′-sugar position. When these modified ODNs bind to... -
dedup_wf_001--7387488b176d100ed9aa0bcd3418a5ee
Presentation at the RDA & the humanities. Network meeting in Denmark. Information about the event -
Additional file 6: Figure S5. of Follistatin is a metastasis suppressor in a ...
FST expression is associated with overall survival and metastasis in multiple cohorts of patients with breast cancer. Tumors are stratified into the highest 10% and lowest... -
Design of Organocatalysts for Asymmetric Direct Syn-Aldol Reactions
Two new organocatalysts 3a and 3b, derived from l-leucine and (S)-β-amino alcohols that were prepared from l-valine, were designed and afforded the direct syn-aldol reactions of... -
Sensitive and Convenient Yeast Reporter Assay for High-Throughput Analysis by...
The yeast reporter assay has been widely used in various applications such as detection of endocrine disruptors and analysis of protein−protein interactions by the yeast... -
Reactions of α,α‘-Dihydroxy Ketones with Phosgene. Structural Requirements fo...
α,α‘-Dihydroxy ketones having two OH groups that can come into close proximity react with phosgene in the presence of DMAP to produce 1,3-dioxane-2,5-diones. When covalent... -
r37980778c78--1b7126077cba5fa4d30974e237410b0b
Novel 5-cyclic amine-3-arylsulfonylindazoles were prepared, and several analogues within this class have been identified as high-affinity 5-HT6 receptor ligands with improved... -
Activation of p300 Histone Acetyltransferase by Small Molecules Altering Enzy...
Reversible acetylation of nucleosomal histones and nonhistone proteins play pivotal roles in the regulation of all the DNA templated phenomenon. Dysfunction of the enzymes... -
r37980778c78--846564b65f52c385ecb3cccfd64a98dc
Protein ADP-ribosyltransferases catalyze the transfer of adenosine diphosphate ribose (ADP-ribose) from nicotinamide adenine dinucleotide (NAD) onto specific target proteins.... -
r37980778c78--abf8e30a95480dae802c80ac51f3c098
Mineral-catalyzed decarboxylation reactions are important in both crude oil formation and, increasingly, biofuel production. In this study we examined decarboxylation reactions... -
r37980778c78--bf2c1a7fa126b07a7d5ef3333acbb9b0
Mixtures of butyllithium and copper iodide prepared in toluene react with α,β-unsaturated ketones predominantly in a 1,2-fashion. Addition of various ethers to the system... -
r37980778c78--d5e220127c35216d97539432c1be8dbd
A rhodamine-based fluorescent and colorimetric chemodosimeter for the rapid detection of Hg2+ ions in aqueous media was developed. The system, which utilizes an irreversible... -
Application of Stereoselective Ether Transfer to the Synthesis of Isotactic P...
An efficient, convergent synthetic strategy has been developed which enables the synthesis of a series of naturally occurring isotactic polymethoxy compounds. Ether transfer... -
r37980778c78--b79c35a80eef834a072e39bc7e6a30c2
The CAMAG thin-layer chromatography mass spectrometer (TLC−MS) interface has been assessed as a tool for the direct quantitative bioanalysis of drugs from dried blood spot (DBS)... -
r37980778c78--e88f8d488d533574ad314f400c833006
Benzheterazole derivatives with ethylene and phenyl linkers have been studied as model compounds to understand the role of (i) aromatic and heteroaromatic rings on the...
