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Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,...
Efforts to identify a suitable follow-on compound to razaxaban (compound 4) focused on modification of the carboxamido linker to eliminate potential in vivo hydrolysis to a... -
Catalytic Carbon−Halogen Bond Activation: Trends in Reactivity, Selectivity,...
We have theoretically studied the oxidative addition of all halomethanes CH3X (with X = F, Cl, Br, I, At) to Pd and PdCl-, using both nonrelativistic and... -
r37980778c78--56fcee8741a21a8729fa2db393bd30b0
Design, synthesis, and in vitro bioevaluation of a new class of potential dual PPARα and γ agonists discovered through a structure-driven design paradigm are described. The... -
Aryl Bridged 1-Hydroxypyridin-2-one: Effect of the Bridge on the Eu(III) Sens...
The efficiency of Eu3+ luminescence by energy transfer from an antenna ligand can be strongly dependent on the metal ion coordination geometry. The geometric component of the... -
r37980778c78--fe4e83e064bdf00dc834ea490c40288c
A ratiometric fluorescent biosensor for Hg2+ is constructed from the MerR protein and a duplex DNA containing a pyrene excimer. -
r37980778c78--6aa789157cd7338db059b4619ee64ff7
A Path Sampling Study of Ru-Hydride-Catalyzed H2 Hydrogenation of Ethylene -
Nitration of the tumor suppressor protein, p53, at tyrosine 327 promotes p53 ...
Previous studies demonstrate that nitric oxide (NO) promotes p53 transcriptional activity by a classical DNA damage responsive mechanism involving activation of ATM/ATR and... -
Metal−Metal Multiple Bonds in Early/Late Heterobimetallics Support Unusual Tr...
Reduction of Zr/Co heterobimetallic complexes ICo(MesNPiPr2)3ZrCl (1) and ICo(iPrNPiPr2)3ZrCl (2) with excess Na/Hg under N2, followed by subsequent benzene extraction to remove... -
dedup_wf_001--4ece1184a0fe713f618e18f0c5495ec8
Figure S1. The screeplot for the Eigenvalue of the different numbers of factors. The red line indicate the cut-off at Eigenvalueâ=â1.0. (PPTX 53 kb) -
r37980778c78--45c77806280e278526960e808d2b7b2b
Electrolysis of benzylthiocyanate, benzyl chloride, p-methylbenzyl chloride, p-methoxybenzyl chloride, or toluene in acetonitrile, at platinum electrodes in a two compartments... -
r37980778c78--566516baee56754d67c275c2225a172b
We previously prepared the oligonucleotides (ODNs) conjugated to an anthraquinone (AQ) group via one carbon linker at the 2′-sugar position. When these modified ODNs bind to... -
The Linkage of Catalysis and Regulation in Enzyme Action. Fluoropyruvate as a...
Pyruvate decarboxylase, a thiamin-diphosphate (ThDP) dependent enzyme from the yeast Saccharomyces cerevisiae (SCPDC), catalyzes the conversion of fluoropyruvate to carbon... -
Additional file 16: Figure S7. of MitoRS, a method for high throughput, sensi...
Coverage drop at the position 310 human C-stretch. The human sample #12878 from the CEPH family 1463 was sequenced either following the pipeline described in this paper or from... -
Ventajas del formato ePub para la difusión de contenidos en Humanidades: just...
Una versión en pdf del contenido está disponible en https://doi.org/10.5281/zenodo.2580057 -
dedup_wf_001--b57a9b11d320b588ac8d24b054557cd6
Figure S2. Chromatogram showing the SDHx mutations found in GISTs (T) and in normal tissue (N) in cases 42–48. Case 42: heterozygous SDHA exon 5 mutation in normal tissue and... -
A Ti<sub>2</sub>Ru<sub>2</sub>Pd<sub>2</sub> Oxo−Sulfido Cluster Synthesized ...
A Ti2Ru2Pd2 Oxo−Sulfido Cluster Synthesized by Linking Two Rationally Preorganized TiRuPdS2 Heterotrimetallic Units with an Oxo Ligand: Its Reaction with an Alkyne -
Reactivity of Aluminum Cluster Anions with Water: Origins of Reactivity and M...
The reactivity of aluminum anion clusters with water was found to exhibit variations with size, with some clusters exhibiting negligible reactivity, others absorbing one or more... -
Damage potential of Drosophila suzukii and development of phytosanitary measu...
Slide of the Euphresco project 'Damage potential of Drosophila suzukii and development of phytosanitary measures' (DROSKII) Project funded through the Euphresco network -
Gas-Phase Deprotonation of <i>p</i>-Hydroxybenzoic Acid Investigated by IR Sp...
Gas-Phase Deprotonation of p-Hydroxybenzoic Acid Investigated by IR Spectroscopy: Solution-Phase Structure Is Retained upon ESI -
Design of Organocatalysts for Asymmetric Direct Syn-Aldol Reactions
Two new organocatalysts 3a and 3b, derived from l-leucine and (S)-β-amino alcohols that were prepared from l-valine, were designed and afforded the direct syn-aldol reactions of...
