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Transcriptionally promiscuous "blurry" promoters in Tc1/mariner transposons a...
Abstract Background We have recently described a peculiar feature of the promoters in two Drosophila Tc1-like elements, Bari1 and Bari3. The AT-richness and the presence of weak... -
Origin, evolution and conservation of the honey bees from La Palma Island (Ca...
Genetic studies have shown a significant hybridization of local populations of Apis mellifera in the Canary Islands, as a consequence of queen importation. Since La Palma Island... -
Capturing the diversity of the human gut microbiota through culture-enriched ...
Abstract Background The human gut microbiota has been implicated in most aspects of health and disease; however, most of the bacteria in this community are considered... -
Characterization of a strong and constitutive promoter from the Arabidopsis s...
Abstract Background Transgenic technology has become an important technique for crop genetic improvement. The application of well-characterized promoters is essential for... -
TSS seq based core promoter architecture in blood feeding Tsetse fly (Glossin...
Abstract Background Transcription initiation regulation is mediated by sequence-specific interactions between DNA-binding proteins (transcription factors) and cis-elements,... -
Production of human pro-relaxin H2 in the yeast Pichia pastoris
Abstract Background Initially known as the reproductive hormone, relaxin was shown to possess other therapeutically useful properties that include extracellular matrix... -
Production of rosmarinic acid and correlated gene expression in hairy root cu...
Rosmarinic acid (RA) is an active constituent of Ocimum basilicum. It has been shown that hairy root production (measured as dry weight) improves when green basil (O. basilicum... -
Sex-specific changes in gene expression in response to estrogen pollution aro...
Abstract The synthetic 17α-ethinylestradiol (EE2) is a common estrogenic pollutant that has been suspected to affect the demography of river-dwelling salmonids. One possibility... -
Efficient and mild swern oxidation using a new sulfoxide and <i>bis</i>(trich...
A new type of sulfoxide, 4-(2-(2-(methylsulfinyl) ethyl)-4-nitrophenyl)- morpholine (I) was designed and prepared in good yield. Upon the combination of I andbis... -
Metatranscriptomic and comparative genomic insights into resuscitation mechan...
Abstract Background The pure culture of prokaryotes remains essential to elucidating the role of these organisms. Scientists have reasoned that hard to cultivate microorganisms... -
Retinoid acid-induced microRNA-31-5p suppresses myogenic proliferation and di...
Abstract Background We previously reported that Wnt5a/CaMKIIδ (calcium/calmodulin-dependent protein kinase II delta) pathway was involved in the embryonic tongue deformity... -
Ectopic expression of citrus UDP-GLUCOSYL TRANSFERASE gene enhances anthocyan...
Abstract Background Citrus fruits are consumed freshly or as juice to directly provide various dietary flavonoids to humans. Diverse metabolites are present among Citrus genera,... -
The differences between gonadal and extra-gonadal malignant teratomas in both...
Abstract Background A tumor comprising of different types of tissues (such as hair, muscle, bone, etc.) is known as a teratoma. It is a type of germ cell (cells that make sperm... -
Etmopteridae bioluminescence: dorsal pattern specificity and aposematic use
Abstract Background In the darkness of the ocean, an impressive number of taxa have evolved the capability to emit light. Many mesopelagic organisms emit a dim ventral glow that... -
A unique cluster of roo insertions in the promoter region of a stress respons...
Abstract Transposable elements (TEs) are not randomly distributed in the genome. A genome-wide analysis of the D. melanogaster genome found that differences in TE density across... -
Effects of hypoxia and hyperoxia on the differential expression of VEGF-A iso...
Abstract Dysregulation of VEGF-A bioavailability has been implicated in the development of lung injury/fibrosis, exemplified by Idiopathic Pulmonary Fibrosis (IPF). VEGF-A is a... -
A novel close-circulating vapor stripping-vapor permeation technique for boos...
Abstract Background Butanol derived from renewable resources by microbial fermentation is considered as one of not only valuable platform chemicals but alternative advanced... -
TGFβ1-induced SMAD2/3 and SMAD1/5 phosphorylation are both ALK5-kinase-depend...
Abstract Background Dysregulated transforming growth factor β (TGFβ) signaling is implicated in osteoarthritis development, making normalizing TGFβ signaling a possible therapy....