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Oxidative stress and premature senescence in corneal endothelium following pe...
Abstract Background The purpose of this study was to address the question of how the premature senescence process may affect corneal endothelium after penetrating keratoplasty,... -
An analysis of SPECT/CT non-visualization of sentinel lymph nodes in renal tu...
Abstract Background Sentinel lymph node biopsy (SLNB) after intratumoral injection of 99mTc labeled nanocolloid and imaging with scintigraphy and SPECT/CT in renal tumors is... -
Scl-Ab reverts pro-osteoclastogenic signalling and resorption in estrogen def...
Abstract Background Neutralising antibodies to sclerostin (Scl-Ab) have shown significant potential to induce bone formation and decrease bone resorption, increase strength and... -
Comparative analyses of the in vivo induction and transmission of α-synuclein...
Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central... -
Incidence and diagnosis of Acute kidney injury in hospitalized adult patients...
Abstract Background Acute kidney injury (AKI) places a heavy burden on the healthcare system in China and is usually misdiagnosed. However, there are limited studies that have... -
Acute kidney injury prediction in cardiac surgery patients by a urinary pepti...
Abstract Background Acute kidney injury (AKI) is a prominent problem in hospitalized patients and associated with increased morbidity and mortality. Clinical medicine is... -
Anesthesiologists as perioperative hospitalists and outcomes in patients unde...
Abstract Background Perioperative care has been identified as an area of wide variability in quality, with conflicting models, and involving multiple specialties. In 2014, the... -
Dimethyl fumarate attenuates reactive microglia and long-term memory deficits...
Abstract Background Systemic inflammation is associated with increased cognitive decline and risk for Alzheimer’s disease. Microglia (MG) activated during systemic inflammation... -
Plasma matrix metalloproteinases are associated with incident cardiovascular ...
Abstract Background Altered regulation of extracellular matrix remodeling by matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase (TIMP) may contribute to... -
Perioperative surgery- and anaesthesia-related risks of laparoscopic Roux-en-...
Abstract Background Conservative obesity treatment often leads to limited results. Bariatric surgery is highly efficient, but the candidates are at risk of developing... -
iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated d...
Abstract Background Previous research indicated that nitric oxide synthase (NOS) is the key molecule for S-nitrosylation of ryanodine receptor 1 (RyR1) in DMD model mice (mdx... -
Long-term survival and prognostic factors for locally advanced renal cell car...
Abstract Background Previous related studies have mainly focused on renal cell carcinoma (RCC) with venous tumor thrombus, specifically inferior vena cava tumor thrombus with... -
Cumulative fluid accumulation is associated with the development of acute kid...
Abstract Background Acute kidney injury (AKI) is common in patients in the intensive care unit (ICU) and may be present on admission or develop during ICU stay. Our objectives... -
Configurations for obtaining in-consultation assistance from supervisors in g...
Abstract Background General practice (GP) trainees may seek supervisor assistance to complete their patient consultations. This in-consultation assistance plays a key role in... -
Distinct core promoter codes drive transcription initiation at key developmen...
Abstract Background Development is largely driven by transitions between transcriptional programs. The initiation of transcription at appropriate sites in the genome is a key... -
Risk factors of renal dysfunction and their interaction in level-low lead exp...
Abstract Background To explore the effect of low-level lead exposure on renal dysfunction in paint works, and analyze the interaction between low-level lead exposure and other... -
MiR-1-3p that correlates with left ventricular function of HCM can serve as a...
Abstract Background MicroRNAs (miRNAs) are non-coding RNAs that function as regulators of gene expression and thereby contribute to the complex disease phenotypes. Hypertrophic... -
Long-term changes in renal function after treatment initiation and the import...
Abstract Background The present study aimed to investigate associations between long-term renal function, whether IgG4-related tubulointerstitial nephritis (TIN) was diagnosed... -
Hemodynamic impacts of flow diverter devices on the ophthalmic artery
Abstract Background Flow diverter devices are increasingly used for endovascular treatment of internal carotid artery aneurysms. Treatment of ophthalmic segment aneurysms with... -
Effect of treatment with a JAK2-selective inhibitor, fedratinib, on bone marr...
Abstract Background Progressive bone marrow fibrosis (BMF) is a cardinal feature of many myeloproliferative neoplasms (MPNs) and there is a documented association between the...