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MRI of trunk muscles and motor and respiratory function in patients with myot...
Abstract Background Myotonic Dystrophy 1 (DM1) causes progressive myopathy of extremity muscles. DM1 may also affect muscles of the trunk. The aim of this study was to... -
Comparison of biochemical parameters among DPP4 inhibitor users and other ora...
Abstract Background Higher efficacy of incretin-based therapies for type 2 diabetes mellitus has been reported from Asia. Pancreatitis and hepatitis have also been suspected to... -
Newborn and childhood differential DNA methylation and liver fat in school-ag...
Abstract Background Non-alcoholic fatty liver disease is the most common chronic liver disease in children in western countries. Adverse early-life exposures are associated with... -
Urinary proteomics for prediction of mortality in patients with type 2 diabet...
Abstract Background The urinary proteomic classifier CKD273 has shown promise for prediction of progressive diabetic nephropathy (DN). Whether it is also a determinant of... -
eRegistries: indicators for the WHO Essential Interventions for reproductive,...
Abstract Background Electronic health registries â eRegistries - can systematically collect relevant information at the point of care for reproductive, maternal, newborn and... -
Assessing quality of newborn care at district facilities in Malawi
Abstract Background Malawi is celebrated as one of the few countries in sub-Saharan Africa to meet the Millennium Development Goal of reducing under-5 mortality by two-thirds... -
Breast milk DHA levels may increase after informing women: a community-based ...
Abstract Background Docosahexaenoic acid (DHA), an omega-3 fatty acid found in breast milk, has many health benefits for both mother and baby. A 2007 meta-analysis found U.S.... -
PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma
Abstract Background The Wnt/β-catenin pathway has a key role in regulating cellular processes and its aberrant signaling can lead... -
Proteomics analysis identifies new markers associated with capillary cerebral...
Abstract Alzheimer’s disease (AD) is characterized by amyloid beta (Aβ) deposits as plaques in the parenchyma and in the walls of cortical and leptomeningeal blood vessels of... -
Epithelial and interstitial Notch1 activity contributes to the myofibroblasti...
Abstract Background Notch1 signalling is a stem-cell-related pathway that is essential for embryonic development, tissue regeneration and organogenesis. However, the role of... -
Systematic mapping of existing tools to appraise methodological strengths and...
Abstract Background Qualitative evidence synthesis is increasingly used alongside reviews of effectiveness to inform guidelines and other decisions. To support this use, the... -
The cotton GhWIN2 gene activates the cuticle biosynthesis pathway and influen...
Abstract Background Metabolic pathways are interconnected and yet relatively independent. Genes involved in metabolic modules are required for the modules to run. Study of the... -
Cytokine pre-activation of cryopreserved xenogeneic-free human mesenchymal st...
Abstract Background Human mesenchymal stem/stromal cells (hMSCs) represent a promising therapeutic strategy for ventilator-induced lung injury (VILI) and acute respiratory... -
Sensitivity of various adiposity indices in identifying cardiometabolic disea...
Abstract Background Obesity is a recognized risk factor for various cardiometabolic diseases and several indices are used clinically to assess overall cardiometabolic risk. This... -
Improving palliative care in selected settings in England using quality indic...
Abstract Background There is a gap between readily available evidence of best practice and its use in everyday palliative care. The IMPACT study evaluated the potential of... -
Point-of-care testing for emergency assessment of coagulation in patients tre...
Abstract Background Point-of-care testing (POCT) of coagulation has been proven to be of great value in accelerating emergency treatment. Specific POCT for direct oral... -
Exposure to Perflouroalkyl acids and foetal and maternal thyroid status: a re...
Abstract Background Exposure to perfluorinated-alkyl-acids (PFAAs) is ubiquitous. PFAAs are hormone-disrupting compounds that are strongly suspected to affect... -
C-reactive protein mediates the association between leisure-time physical act...
Abstract Background Although previous studies have reported the benefits of physical activity (PA) to lung function in middle-aged and older adults, the biological mechanisms... -
Is daily physical activity affected by dynamic hyperinflation in adults with ...
Abstract Background The aim of this study was to investigate the relationship between dynamic hyperinflation and daily physical activity (DPA) in adults with cystic fibrosis... -
The prevalence of gastric heterotopia of the proximal esophagus is underestim...
Abstract Background The previously reported prevalence of gastric heterotopia in the cervical esophagus, also termed inlet patch (IP), varies substantially, ranging from 0.18 to...
