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Aberrant activation of NF-κB signaling in mammary epithelium leads to abnorma...
Abstract Background Approximately 1 in 5 women diagnosed with breast cancer are considered to have in situ disease, most often termed ductal carcinoma in situ (DCIS). Though... -
Carotid arterial wall inflammation in peripheral artery disease is augmented ...
Abstract Background Patients with peripheral artery disease (PAD) are at increased risk of secondary events, which is exaggerated in the presence of type 2 diabetes mellitus.... -
Dynamic light sheet generation and fluorescence imaging behind turbid media
Abstract Background Light sheet microscopy became a popular tool allowing fast imaging with reduced out of focus light. However, when light penetrates turbid media such as... -
Comparison of peri-implant soft tissue and crestal bone status of dental impl...
Abstract Background Clinicoradiographic status of narrow-diameter implants (NDIs) among patients with prediabetes and type 2 diabetes mellitus (DM) is scarce. The aim was to... -
Epidural adipose tissue-derived mesenchymal stem cell activation induced by l...
Abstract Background Spinal metastasis is a major challenge in patients with advanced lung cancer, but the mechanisms in the organotropism of metastasis are still unclear.... -
Transcriptome analysis reveals regional and temporal differences in mucosal i...
Abstract Background Postnatal development of the mammalian mucosal immune system is crucial for responding to the rapid colonization by commensal bacteria and possible exposure... -
Skin autofluorescence is associated with inappropriate left ventricular mass ...
Abstract Background Enhanced advanced glycation end products deposition within myocardial tissue may cause diastolic dysfunction. However, whether this is related to left... -
Early strong intrathecal inflammation in cerebellar type multiple system atro...
Abstract Background The pathology of multiple system atrophy cerebellar-type (MSA-C) includes glial inflammation; however, cerebrospinal fluid (CSF) inflammatory cytokine... -
The crucial role of PpMYB10.1 in anthocyanin accumulation in peach and relati...
Abstract Background Red coloration of fruit skin is one of the most important traits in peach (Prunus persica), and it is mainly due to the accumulation of anthocyanins. Three... -
Improved co-registration of ex-vivo and in-vivo cardiovascular magnetic reson...
Abstract Background Ex-vivo cardiovascular magnetic resonance (CMR) imaging has played an important role in the validation of in-vivo CMR characterization of pathological... -
Risk factors for iliopsoas impingement after total hip arthroplasty using a c...
Abstract Background The relationship between collar design of a femoral component and iliopsoas impingement (IPI) after total hip arthroplasty (THA) is still underrecognized.... -
The efficacy of transcutaneous electrical nerve stimulation on the improvemen...
Abstract Background In patients with peripheral arterial disease (PAD), walking improvements are often limited by early pain onset due to vascular claudication. It would thus... -
Deletion of Nlrp3 protects from inflammation-induced skeletal muscle atrophy
Abstract Background Critically ill patients develop atrophic muscle failure, which increases morbidity and mortality. Interleukin-1β (IL-1β) is activated early in sepsis.... -
Umbilical cord/placenta-derived mesenchymal stem cells inhibit fibrogenic act...
Abstract Background The lack of anti-fibrotic agents targeting intestinal fibrosis is a large unmet need in inflammatory bowel diseases, including Crohn’s disease and ulcerative... -
Effects of isoflurane, remifentanil and dexmedetomidine on selected EEG param...
Abstract Background The aim of this prospective and complete cross-over study was to evaluate the effects of isoflurane, remifentanil and dexmedetomidine on EEG parameters... -
Cellulase hyper-production by Trichoderma reesei mutant SEU-7 on lactose
Abstract Background The induction of cellulase production by insoluble carbon source cellulose was a common and efficient strategy, but has some drawbacks, such as difficult... -
Assignment of sigma factors of RNA polymerase to promoters in Corynebacterium...
Abstract Corynebacterium glutamicum is an important industrial producer of various amino acids and other metabolites. The C. glutamicum genome encodes seven sigma subunits... -
Assessment of longitudinal distribution of subclinical atherosclerosis in fem...
Abstract Background Lower extremity peripheral artery disease has become a significant health burden worldwide. Since the treatment strategies can be different if... -
Computational fluid dynamic analysis of physical forces playing a role in bra...
Abstract Background Organoid cultivation in suspension culture requires agitation at low shear stress to allow for nutrient diffusion, which preserves tissue structure.... -
Evaluation of human primary intestinal monolayers for drug metabolizing capab...
Abstract Background The intestinal epithelium is a major site of drug metabolism in the human body, possessing enterocytes that house brush border enzymes and phase I and II...
