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Guideline-based quality indicators—a systematic comparison of German and inte...
Abstract Background Evidence-based clinical practice guidelines (CPGs) are relevant sources for generating quality indicators (QIs). The objective of this study was to compare... -
Variability of Uncrossmatched Blood Use by Helicopter EMS Programs in the Uni...
Study Objective: Some helicopter emergency medical services (HEMS) maintain an independent supply of blood for use during transport, although practice is variable and not well... -
Impact of radiographer immediate reporting of chest X-rays from general pract...
Abstract Background Diagnostic capacity and suboptimal logistics are consistently identified as barriers to timely diagnosis of cancer, especially lung cancer. Immediate chest... -
Bursicon-α subunit modulates dLGR2 activity in the adult <i>Drosophila</i> me...
Bursicon is the main regulator of post molting and post eclosion processes during arthropod development. The active Bursicon hormone is a heterodimer of Burs-α and Burs-... -
Consensus of potential modifiable prognostic factors for persistent pain afte...
Abstract Background Identify and establish consensus regarding potential prognostic factors for the development of chronic pain after a first episode of idiopathic,... -
AHRR methylation in heavy smokers: associations with smoking, lung cancer ris...
Abstract Background A low level of methylation at cg05575921 in the aryl-hydrocarbon receptor repressor (AHRR) gene is robustly associated with smoking, and some studies have... -
Centralising specialist cancer surgery services in England: survey of factors...
Abstract Background The centralisation of specialist cancer surgical services across London Cancer and Greater Manchester Cancer, England, may significantly change how patients... -
Investigating factors associated with success of breastfeeding in first-time ...
Abstract Background We investigated the possible risk factors that could influence the likelihood of breastfeeding at 5 to 9 weeks postpartum with our primary aim being to... -
Confident gene activity prediction based on single histone modification H2BK5...
Abstract Background The histones in the core of nucleosomes may be subject to covalent post-transcriptional modifications. These modifications are thought to correlate with and... -
Two subphenotypes of septic acute kidney injury are associated with different...
Abstract Background The pathophysiology of septic acute kidney injury is inadequately understood. Recently, subphenotypes for... -
Bursicon-α subunit modulates dLGR2 activity in the adult <i>Drosophila melano...
Bursicon is the main regulator of post molting and post eclosion processes during arthropod development. The active Bursicon hormone is a heterodimer of Burs-α and Burs-β.... -
A new set of cluster driven composite development indicators
Abstract Composite development indicators used in policy making often subjectively aggregate a restricted set of indicators. We show, using dimensionality reduction techniques,... -
Sex differences in cardiovascular epigeneticsâ a systematic review
Abstract Background Differences in cardiovascular diseases are evident in men and women throughout life and are mainly attributed to the presence of sex hormones and... -
Meta-analysis of GWAS on both Chinese and European populations identifies GPR...
Abstract Background Systemic lupus erythematous (SLE) is a complex autoimmune disease with female predominance, particularly affecting those of childbearing age. We performed... -
PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma
Abstract Background The Wnt/β-catenin pathway has a key role in regulating cellular processes and its aberrant signaling can lead... -
Peripheral blood metabolome predicts mood change-related activity in mouse mo...
Abstract Bipolar disorder is a major mental illness characterized by severe swings in mood and activity levels which occur with variable amplitude and frequency. Attempts have... -
The regional association between bronchiectasis and lung cancer in chest CT
Abstract Background Limited studies have examined the association between lung cancer and bronchiectasis (BE). This study evaluated the regional association between BE and lung... -
Fidelity of DNA polymerases in the detection of intraindividual variation of ...
Here we investigated the consequences of PCR amplification errors in the identification of intraindividual mtDNA variation. The bumblebee Bombus morio was chosen as model for... -
Abdominal obesity increases metabolic risk factors in non-obese adults: a Hun...
Abstract Background The prevalence of abdominal obesity is increasing worldwide. Adults with abdominal obesity have been reported to have increased risk of cardiometabolic... -
Low priority of obesity education leads to lack of medical students’ prepared...
Abstract Background Physicians are currently unprepared to treat patients with obesity, which is of great concern given the obesity epidemic in the United States. This study...
