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Long-term survival and prognostic factors for locally advanced renal cell car...
Abstract Background Previous related studies have mainly focused on renal cell carcinoma (RCC) with venous tumor thrombus, specifically inferior vena cava tumor thrombus with... -
Reduced expression of miR-146a in human bronchial epithelial cells alters neu...
Abstract Background The role of miRNAs in the pathogenesis and determining the phenotypes of asthma is not fully elucidated. miR-146a has been previously shown to suppress... -
Downregulation of miR-204 expression defines a highly aggressive subset of Gr...
Abstract Genome-wide expression profiling studies have identified four core molecular subgroups of medulloblastoma: WNT, SHH, Group 3 and Group 4. Molecular markers are... -
Connexin32 plays a crucial role in ROS-mediated endoplasmic reticulum stress ...
Abstract Background Ischemia–reperfusion (I/R)-induced acute kidney injury (AKI) not only prolongs the length of hospital stay, but also seriously affects the patient’s survival... -
Mesenchymal stem cell-derived exosomes protect beta cells against hypoxia-ind...
Abstract Background Hypoxia is a major cause of beta cell death and dysfunction after transplantation. The aim of this study was to investigate the effect of exosomes derived... -
ICU survival and need of renal replacement therapy with respect to AKI durati...
Abstract Background Transient and persistent acute kidney injury (AKI) could share similar physiopathological mechanisms. The objective of our study was to assess prognostic... -
miR-140-5p regulates the odontoblastic differentiation of dental pulp stem ce...
Abstract Background MicroRNAs (miRNAs) play a key role in regulating cell differentiation. In the present study, we aimed to explore the role of miR-140-5p in odontoblastic... -
Umbilical cord/placenta-derived mesenchymal stem cells inhibit fibrogenic act...
Abstract Background The lack of anti-fibrotic agents targeting intestinal fibrosis is a large unmet need in inflammatory bowel diseases, including Crohn’s disease and ulcerative... -
Chip-on-the-tip compact flexible endoscopic epifluorescence video-microscope ...
We demonstrate a 60 mg light video-endomicroscope with a cylindrical shape of the rigid tip of only 1.6 mm diameter and 6.7 mm length. A novel implementation method of the... -
Eukaryotic elongation factor-2 kinase expression is an independent prognostic...
Abstract Background Prognostication of patients with colorectal cancer (CRC) currently relies on tumor-node-metastasis (TNM) staging but clinical outcomes of patients of the... -
Effects of hypoxia and hyperoxia on the differential expression of VEGF-A iso...
Abstract Dysregulation of VEGF-A bioavailability has been implicated in the development of lung injury/fibrosis, exemplified by Idiopathic Pulmonary Fibrosis (IPF). VEGF-A is a... -
The preventive effect of resiniferatoxin on the development of cold hypersens...
Abstract Background Resiniferatoxin (RTX) is a potent analog of capsaicin and activates transient receptor potential (TRP) vanilloid type (TRPV) 1. In the current study, we... -
miR-375 mediates the CRF signaling pathway to regulate catecholamine biosynth...
Corticotropin-releasing-factor (CRF) is a key regulator of catecholamines (CATs) biosynthesis in the adrenal gland. Furthermore, miR-375 has been confirmed to be localized in... -
Deltopectoral flap revisited for reconstruction surgery in patients with adva...
Abstract Background We present the cases of 2 patients with invasive thyroid cancer, who underwent reconstructive surgery using a deltopectoral flap. Although the overall rate...
