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Omalizumab in patients with severe asthma and persistent sputum eosinophilia
Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who... -
Additional file 7: of The prominent alteration in transcriptome and metabolom...
Table S7. The homologous genes between M. bovis BCG and M. tuberculosis H37Rv. (XLS 1840 kb) -
Visual axial PSF of diffractive trifocal lenses
The ophthalmic applications of a diffractive trifocal lens design with adjustable add powers and light distribution in the foci are investigated. Axial PSFs of the trifocal... -
Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate...
Abstract Background Dexketoprofen trometamol plus tramadol hydrochloride is a new oral combination of two analgesics, which have different mechanisms of action for the treatment... -
Resveratrol mediates mechanical allodynia through modulating inflammatory res...
Abstract Background Neuropathic pain (NeuP) is a chronic and challenging clinical problem, with little effective treatment. Resveratrol has shown neuroprotection by inhibiting... -
Lytic polysaccharide monooxygenases and other oxidative enzymes are abundantl...
Abstract Background Starch is the second most abundant plant-derived biomass and a major feedstock in non-food industrial applications and first generation biofuel production.... -
ERα-36 regulates progesterone receptor activity in breast cancer
Abstract Background Alterations in estrogen and progesterone signaling, via their respective receptors, estrogen receptor alpha (ERα) and progesterone receptor (PR),... -
Highly active promoters and native secretion signals for protein production d...
Abstract Background The filamentous ascomycete Aspergillus niger is used in many industrial processes for the production of enzymes and organic acids by batch and fed-batch... -
High-intensity exercise to promote accelerated improvements in cardiorespirat...
Abstract Background African Americans have a disproportionate prevalence and incidence of type 2 diabetes compared with Caucasians. Recent evidence indicates that low... -
The effects of green cardamom on blood glucose indices, lipids, inflammatory ...
Abstract Background The relationship between dietary components and nonalcoholic fatty liver disease (NAFLD) needs to be further investigated. The potential health benefits of... -
Designing gene panels for tumor mutational burden estimation: the need to shi...
Abstract Tumor mutational burden (TMB) assessment is at the forefront in precision medicine. The TMB could represent a biomarker for immune checkpoint inhibitors (ICIs)... -
Pain rates in general population for the period 1991–2015 and 10-years predic...
Abstract Background Pain is a common symptom, often associated with neurological and musculoskeletal conditions, and experienced especially by females and by older people. The... -
Feasibility and acceptance of exercise recommendations (10,000 steps a day) w...
Abstract Background Benefits of exercise to prevent non-communicable diseases are well-documented. Limited data exists to promote physical activity in healthy but sedentary... -
Supplement of microbiota-accessible carbohydrates prevents neuroinflammation ...
Abstract Background Western pattern diets induce neuroinflammation and impair cognitive behavior in humans and animals. Neuroinflammation and cognitive impairment have been... -
Micronutrient-rich dietary intake is associated with a reduction in the effec...
Abstract Background Informal recycling of electronic waste (e-waste) releases particulate matter (PM) into the ambient air. Human exposure to PM has been reported to induce... -
Examining the role of unmeasured confounding in mediation analysis with genet...
Abstract Background In mediation analysis if unmeasured confounding is present, the estimates for the direct and mediated effects may be over or under estimated. Most methods... -
The neuroregenerative effects of topical decorin on the injured mouse cornea
Abstract Background The cornea is innervated with a rich supply of sensory nerves that play important roles in ocular surface health. Any injury or pathology of the corneal... -
Lack of association between circulating apelin level and frailty-related func...
Abstract Background Apelin, an active endogenous peptide, has been recently receiving great attention as a promising target for antiaging intervention, primarily based on... -
Increased accuracy of starch granule type quantification using mixture distri...
Abstract Background The proportion of granule types in wheat starch is an important characteristic that can affect its functionality. It is widely accepted that granule types... -
Untargeted metabolomics reveals the effect of lovastatin on steroid-induced n...
Abstract Purpose Lovastatin is an important medicine and it shows a significant effect against glucocorticoid-induced necrosis of the femoral head. This study aimed to...
