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Thermo-optic tuning and switching in SOI waveguide Fabry-Perot microcavities
Compact silicon-on-insulator (SOI) waveguide thermo-optically tunable Fabry-Perot microcavities with silicon/air Bragg mirrors are demonstrated. Quality factors of Q=4,584 are... -
Development of a benchmark tool for cancer centers; results from a pilot exer...
Abstract Background Differences in cancer survival exist between countries in Europe. Benchmarking of good practices can assist cancer centers to improve their services aiming... -
The NuA4 acetyltransferase and histone H4 acetylation promote replication rec...
Abstract Background Histone acetylation plays an important role in DNA replication and repair because replicating chromatin is subject to dynamic changes in its structures.... -
Human laminin-111 and laminin-211 protein therapy prevents muscle disease pro...
Abstract Background Laminin-α2-related congenital muscular dystrophy (LAMA2-CMD) is a devastating genetic disease caused by mutations in the LAMA2 gene. These mutations result... -
ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis p...
Abstract Background Transcription factor binding, histone modification, and chromatin accessibility studies are important approaches to understanding the biology of gene... -
Grading and assessment of clinical predictive tools for paediatric head injur...
Abstract Background Many clinical predictive tools have been developed to diagnose traumatic brain injury among children and guide the use of computed tomography in the... -
International Analgesia, Sedation, and Delirium Practices: a prospective coho...
Abstract Background While understanding of critical illness and delirium continue to evolve, the impact on clinical practice is often unknown and delayed. Our purpose was to... -
Combining structural and bioactivity-based fingerprints improves prediction p...
Abstract This study aims at improving upon existing activity predictions methods by augmenting chemical structure fingerprints with bio-activity based fingerprints derived from... -
Estimation and monitoring of city-to-city travel times using call detail records
Abstract Whenever someone makes or receives a call on a mobile telephone, a Call Detail Record (CDR) is automatically generated by the operator for billing purposes. CDRs have a... -
Correction to: Goats in the city: prevalence of Giardia duodenalis and Crypto...
In the original publication of this article [1] the supplementary file was missing two primers for the PCR reaction and the PCR conditions of Giardia and Cryptosporidium. In... -
DoGFinder: a software for the discovery and quantification of readthrough tra...
Abstract Background Recent studies have described a widespread induction of transcriptional readthrough as a consequence of various stress conditions in mammalian cells. This... -
Supporting sustained adoption of education innovations: The Designing for Sus...
Abstract Background Every year, significant effort and resources are expended around the world to develop innovative instructional strategies and materials to improve... -
Methods and indicators for measuring patterns of human exposure to malaria ve...
Abstract Background Effective targeting and evaluation of interventions that protect against adult malaria vectors requires an understanding of how gaps in personal protection... -
Precision radiotherapy for non-small cell lung cancer
Abstract Precision medicine is becoming the standard of care in anti-cancer treatment. The personalized precision management of cancer patients highly relies on the improvement... -
Patient decision aids: a content analysis based on a decision tree structure
Abstract Introduction This paper presents the preliminary results of a decision-tree analysis of Patient Decision Aids (PDA). PDAs are online or offline tools used to structure... -
Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without gen...
Abstract Multiplexed single-cell RNA-seq analysis of multiple samples using pooling is a promising experimental design, offering increased throughput while allowing to overcome... -
Controllable Growth of the Graphene from Millimeter-Sized Monolayer to Multil...
Abstract As is well established, mastery to precise control of the layer number, stacking order of graphene, and the size of single-crystal monolayer graphene is very important... -
Causes of the N–S compressional aftershocks of the E–W compressional 2008 Iwa...
Abstract In this study, we investigated the influence of local structural heterogeneities on aftershocks of the 2008 Iwate–Miyagi Nairiku earthquake (M 7.2) that occurred in the... -
GPCR and IR genes in Schistosoma mansoni miracidia
Abstract Background Schistosoma species are responsible for the disease schistosomiasis, a highly prevalent helminthic disease that requires a freshwater snail as intermediate... -
AutoSOME: a clustering method for identifying gene expression modules without...
Abstract Background Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the...