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Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate...
Abstract Background Dexketoprofen trometamol plus tramadol hydrochloride is a new oral combination of two analgesics, which have different mechanisms of action for the treatment... -
Prevalence of Schistosoma mansoni infection and the therapeutic efficacy of p...
Abstract Background Intestinal schistosomiasis is one of the neglected tropical parasitic diseases caused by Schistosoma mansoni. Currently, the control measures for the disease... -
The efficacy of varenicline in achieving abstinence among waterpipe tobacco s...
Abstract Background Waterpipe tobacco smoking has increased among youth across the globe including in the US, and it continues as a common and traditional form of smoking... -
Should statin guidelines consider patient preferences? Eliciting preferences ...
Abstract Background Patient preferences are key parameters to evaluate benefit-harm balance of statins for primary prevention but they are not readily available to guideline... -
Use of biologically-based complementary medicine in breast and gynecological ...
Abstract Background Biologically-based complementary medicines (BB-CAM) including herbs and nutritional supplements are frequently taken by breast- and gynecological cancer... -
The effect of the Xpert MTB/RIF test on the time to MDR-TB treatment initiati...
Abstract Background There are significant delays in initiation of multidrug-resistant tuberculosis (MDR –TB) treatment. The Xpert MTB/RIF test has been shown to reduce the time... -
Prioritising pathogens for the management of severe febrile patients to impro...
Abstract Background Severe febrile illness without a known source (SFWS) is a challenge for clinicians when deciding how to manage a patient, particularly given the wide... -
Prolonged exposure therapy and supportive counselling for posttraumatic stres...
Abstract Background There is a dearth of empirical evidence on the effectiveness of pharmacological and non-pharmacological treatments for adolescents with posttraumatic stress... -
Effects and determinants of tuberculosis drug stockouts in South Africa
Abstract Background The frequent occurrence of medicine stockouts represents a significant obstacle to tuberculosis control in South Africa. Stockouts can lead to treatment... -
A double-masked placebo-controlled trial of azithromycin to prevent child mor...
Abstract Background Biannual, mass azithromycin distribution has previously been shown to reduce all-cause child mortality in sub-Saharan Africa. Subgroup analysis suggested... -
Comparative efficacy between atorvastatin and rosuvastatin in the prevention ...
© 2019 The Author(s). Background: There is no randomized clinical trials with recurrence of atherosclerotic cardiovascular disease (ASCVD) as a major outcome with rosuvastatin.... -
Schistosoma mansoni infection among preschool age children attending Erer Hea...
Abstract Objective Preschool age children (PSAC) are excluded from community based praziquantel treatment programs mainly due to paucity of evidence on the magnitude of... -
Optimal regimens of sulfamethoxazole-trimethoprim for chemoprophylaxis of Pne...
Abstract Background Sulfamethoxazole-trimethoprim (SMX/TMP) is a standard drug for the prophylaxis of Pneumocystis pneumonia (PJP) in immunosuppressed patients with systemic... -
Chinese pediatric Tuina on children with acute diarrhea: study protocol for a...
Abstract Background Acute pediatric diarrhea is one of the most common causes of morbidity and mortality worldwide and seriously affects the health of children. Previous studies... -
Dengue virus causes changes of MicroRNA-genes regulatory network revealing po...
Abstract Background Dengue virus (DENV) is an increasing global health threat and associated with induction of both a long-lived protective immune response and... -
A systematic review of necrotising fasciitis in children from its first descr...
Abstract Background Necrotising fasciitis is a rapidly progressing soft-tissue infection with a low incidence that carries a relevant risk of morbidity and mortality. Although... -
How to eliminate taeniasis/cysticercosis: porcine vaccination and human chemo...
Abstract Background The application of effective vaccines against pig cysticercosis and mass chemotherapy against pig cysticercosis and human taeniasis have shown the... -
PS4DR: a multimodal workflow for identification and prioritization of drugs b...
Abstract Background During the last decade, there has been a surge towards computational drug repositioning owing to constantly increasing -omics data in the biomedical research... -
Quantitative evaluation of the strategy to eliminate human African trypanosom...
Abstract Background The virulent vector-borne disease, Gambian human African trypanosomiasis (HAT), is one of several diseases targeted for elimination by the World Health... -
Amikacin pharmacokinetic/pharmacodynamic in intensive care unit: a prospectiv...
Abstract Background Aminoglycosides have a concentration-dependent therapeutic effect when peak serum concentration (Cmax) reaches eight to tenfold the minimal inhibitory...
