75 items found

Licenses: License Not Specified Tags: 69999 Biological Sciences not elsewhere classified Biotechnology Cell Biology Genetics Physiology Types: other

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    Maternal and cord blood adiponectin levels in relation to post-natal body siz...

    Abstract Background Adiponectin is an adipocyte hormone involved in energy homeostasis and metabolism. However, its role in early infancy is poorly understood. Methods We...
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    Computational fluid dynamic analysis of physical forces playing a role in bra...

    Abstract Background Organoid cultivation in suspension culture requires agitation at low shear stress to allow for nutrient diffusion, which preserves tissue structure....
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    Do fragments and glycosylated isoforms of alpha-1-antitrypsin in CSF mirror s...

    Abstract Background Post-translational modifications (PTMs) generate a tremendous protein diversity from the ~ 20,000 protein-coding genes of the human genome. In chronic pain...
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    Visualization of activity-regulated BDNF expression in the living mouse brain...

    Abstract Altered levels of brain-derived neurotrophic factor (BDNF) have been reported in neurologically diseased human brains. Therefore, it is important to understand how the...
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    Evaluation of human primary intestinal monolayers for drug metabolizing capab...

    Abstract Background The intestinal epithelium is a major site of drug metabolism in the human body, possessing enterocytes that house brush border enzymes and phase I and II...
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    Sensitization profile in patients with respiratory allergic diseases: differe...

    Abstract Background Component-resolved diagnosis (CRD) allows to identify single molecular allergen components, and constitutes a routine practice in many allergy units....
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    Controlling heterologous gene expression in yeast cell factories ...

    Abstract Background Predictable control of gene expression is necessary for the rational design and optimization of cell factories. In the yeast Saccharomyces cerevisiae, the...
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    Ultra-low-dose sequential computed tomography for quantitative lung aeration ...

    Abstract Background Quantitative lung computed tomography (CT) provides fundamental information about lung aeration in critically ill patients. We tested a scanning protocol...
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    Joint association of mammographic density adjusted for age and body mass inde...

    Abstract Background Mammographic breast density, adjusted for age and body mass index, and a polygenic risk score (PRS), comprised of common genetic variation, are both strong...
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    Inhibitory effects of aspirin-triggered resolvin D1 on spinal nociceptive pro...

    Abstract Background Harnessing the actions of the resolvin pathways has the potential for the treatment of a wide range of conditions associated with overt inflammatory...
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    Up-regulation of circulating microRNA-17 is associated with lumbar radicular ...

    Abstract Background Previous studies suggest that regulatory microRNAs (miRs) may modulate neuro-inflammatory processes. The purpose of the present study was to examine the role...
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    Effect of mechanical power on intensive care mortality in ARDS patients

    Abstract Background In ARDS patients, mechanical ventilation should minimize ventilator-induced lung injury. The mechanical power which is the energy per unit time released to...
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    Assessment of the underlying systems involved in standing balance: the additi...

    Abstract Background Closed loop system identification (CLSIT) is a method to disentangle the contribution of underlying systems in standing balance. We investigated whether...
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    Transcriptional analysis of porcine intestinal mucosa infected with Salmonell...

    Abstract Infected pork meat is an important source of non-typhoidal human salmonellosis. Understanding of molecular mechanisms involved in disease pathogenesis is important for...
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    Reference markers of bone turnover for prediction of fracture: a meta-analysis

    Abstract Objective To explore whether bone turnover biomarkers (BTMs), i.e., C-terminal telopeptide of type I collagen (CTX) and procollagen type I aminoterminal propeptide...