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Transcriptional analysis of porcine intestinal mucosa infected with Salmonell...
Abstract Infected pork meat is an important source of non-typhoidal human salmonellosis. Understanding of molecular mechanisms involved in disease pathogenesis is important for... -
Intrapartum uterine activity and neonatal outcomes: a systematic review
Abstract Background Increased uterine activity (UA) may not allow adequate recovery time for foetal oxygenation. Methods The aim of the study was to determine if increased UA... -
FEV1 and FVC and systemic inflammation in a spinal cord injury cohort
Abstract Background Systemic inflammation has been associated with reduced pulmonary function in individuals with and without chronic medical conditions. Individuals with... -
TGFβ1-induced SMAD2/3 and SMAD1/5 phosphorylation are both ALK5-kinase-depend...
Abstract Background Dysregulated transforming growth factor β (TGFβ) signaling is implicated in osteoarthritis development, making normalizing TGFβ signaling a possible therapy.... -
Transpulmonary thermodilution detects rapid and reversible increases in lung ...
Abstract Purpose It has been suggested that, by recruiting lung regions and enlarging the distribution volume of the cold indicator, increasing the positive end-expiratory... -
Ouabain prevents pathological cardiac hypertrophy and heart failure through a...
Abstract Background Use of low doses of digitalis to prevent the development of heart failure was advocated decades ago, but conflicting results of early animal studies... -
Does growth hormone supplementation improve oocyte competence and IVF outcome...
Abstract Background Many studies have demonstrated the benefits of the addition of growth hormone (GH) to the controlled ovarian stimulation protocol in vitro fertilization... -
Plasmonic spectral splitting in multi-resonator-coupled waveguide systems
Spectral splitting is numerically investigated in a metal-insulator-metal plasmonic waveguide coupled with a series of disk cavities for the first time to our best knowledge.... -
Randomized controlled studies on the efficacy of antiarthritic agents in inhi...
Abstract Background As an initial step in the development of a local therapeutic to treat osteoarthritis (OA), a number of agents were tested for their ability to block... -
Prolonged preoperative treatment of acromegaly with Somatostatin analogs may ...
Abstract Background This study aimed to investigate preoperative somatostatin analogs (SSAs) treatment on the surgical outcome in patients with acromegaly. Methods An analysis... -
FNDC5 attenuates obesity-induced cardiac hypertrophy by inactivating JAK2/STA...
Abstract Background Chronic low-grade inflammation and oxidative stress play important roles in the development of obesity-induced cardiac hypertrophy. Here, we investigated the... -
Detection of critical cerebral desaturation thresholds by three regional oxim...
Abstract Background Regional oximetry is increasingly used to monitor post-extraction oxygen status of the brain during surgical procedures where hemodynamic fluctuations are... -
Oleogel-S10 Phase 3 study "EASE" for epidermolysis bullosa: study design and ...
Abstract Background Epidermolysis bullosa (EB) is a group of rare, genetic diseases that affect the integrity of epithelial tissues, most notably the skin. Patients experience... -
Leptin receptor signaling is required for high-fat diet-induced atrophic gast...
Abstract Background Obesity increases the risk for malignancies in various tissues including the stomach. Atrophic gastritis with precancerous lesions is an obesity-associated... -
Microglial depletion and repopulation in brain slice culture normalizes sensi...
Abstract Background Microglia are critical mediators of neuroimmune pathology across multiple neurologic disorders. Microglia can be persistently activated or “primed” by...
