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A complex intervention to improve implementation of World Health Organization...
Background To improve management of severely ill hospitalized patients in low-income settings, the World Health Organization (WHO) established a triage tool called “Quick Check”... -
Using a dynamic adherence Markov model to assess the efficiency of Respirator...
Background Respiratory Medication Therapy Adherence Clinic (RMTAC) is an initiative by the Ministry of Health (MOH) Malaysia to improve patients’ medication adherence, as an... -
What hinders the uptake of computerized decision support systems in hospitals...
Background Advanced Computerized Decision Support Systems (CDSSs) assist clinicians in their decision-making process, generating recommendations based on up-to-date scientific... -
Self-declared stock ownership and association with positive trial outcome in ...
Background Describe the prevalence and types of conflicts of interest (COI) in published randomized controlled trials (RCTs) in general medical journals with a binary primary... -
Adherence to the International Committee of Medical Journal Editors’ (ICMJE) ...
Background Registration of clinical trials is critical for promoting transparency and integrity in medical research; however, trials must be registered in a prospective fashion... -
A phase IIa proof-of-concept, placebo-controlled, randomized, double-blind, c...
Background This study evaluates a novel bronchodilator, S1226, for its efficacy in reversing allergen-induced bronchoconstriction in subjects with mild, allergic asthma. S1226... -
Alk5/Runx1 signaling mediated by extracellular vesicles promotes vascular rep...
Background Pulmonary endothelial cells’ (ECs) injury and apoptotic death are necessary and sufficient for the pathogenesis of the acute respiratory distress syndrome (ARDS),... -
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Background Randomised controlled trials are generally regarded as the ‘gold standard’ experimental design to determine the effectiveness of an intervention. Unfortunately, many... -
Key genes and integrated modules in hematopoietic differentiation of human em...
Background The generation of hematopoietic stem cells (HSCs) and blood cells from human embryonic stem cells (hESCs) is a major goal for regenerative medicine; however, the... -
A randomized matched-pairs study of feasibility, acceptability, and effective...
Background This paper reports on the feasibility, acceptability, and effectiveness of an innovative implementation strategy named “systems consultation” aimed at improving... -
What drives adoption of a computerised, multifaceted quality improvement inte...
Background A computerised, multifaceted quality improvement (QI) intervention for cardiovascular disease (CVD) management in Australian primary healthcare was evaluated in a... -
Sex and cardiovascular disease status differences in attitudes and willingnes...
Background While women are under-represented in research on cardiovascular disease (CVD), little is known about the attitudes of men and women with CVD regarding participation... -
Art therapy is associated with sustained improvement in cognitive function in...
Background Mild cognitive impairment (MCI) is a phase in cognitive decline when it is still possible to intervene to reverse the decline. Cognitive stimulation delivered through... -
Dimensions of sustainability for a health communication intervention in Afric...
Background Sustainability of evidence-based health promotion interventions has received increased research attention in recent years. This paper reports sustainability data from... -
Establishment of xenogeneic serum-free culture methods for handling human den...
Background Currently, ex-vivo handling of stem cells, including transport after harvest and therapeutic preparation, is generally done in culture media containing fetal bovine... -
Minimal sufficient balance randomization for sequential randomized controlled...
Background We describe the implementation of minimal sufficient balance randomization, a covariate-adaptive randomization technique, used for the “Endovascular treatment for... -
A cluster-randomised feasibility trial of a children’s weight management prog...
Background Community-based programmes for children with excess weight are widely available, but few have been developed to meet the needs of culturally diverse populations. We... -
Post-infectious sequelae after Campylobacter enteric infection: a pilot study...
Background Campylobacter is a leading cause of gastroenteritis across the globe caused by the ingestion of contaminated food, water, or contact with animals carrying... -
"I had to somehow still be flexible": exploring adaptations during implementa...
Background Primary care clinics present challenges to implementing evidence-based psychotherapies (EBPs) for depression and anxiety, and frontline providers infrequently adopt... -
A core outcomes set for clinical trials of interventions for young adults wit...
Background Achieving consensus from a range of relevant stakeholders about an agreed set of core outcomes to be measured and reported as a minimum in clinical trials has the...
