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Metabolic characterization of aggressive breast cancer cells exhibiting invas...
Abstract Background Metabolic reprogramming is being recognized as a fundamental hallmark of cancer, and efforts to identify drugs that can target cancer metabolism are... -
Effects of cigarette smoke on barrier function and tight junction proteins in...
Abstract Background Airway epithelial barrier function is maintained by the formation of tight junctions (TJs) and adherens junctions (AJs). Inhalation of cigarette smoke causes... -
Reduced expression of miR-146a in human bronchial epithelial cells alters neu...
Abstract Background The role of miRNAs in the pathogenesis and determining the phenotypes of asthma is not fully elucidated. miR-146a has been previously shown to suppress... -
Musashi2 promotes EGF-induced EMT in pancreatic cancer via ZEB1-ERK/MAPK sign...
Abstract Background Our previous study showed Musashi2 (MSI2) promoted chemotherapy resistance and pernicious biology of pancreatic cancer (PC) by down-regulating Numb and p53.... -
The human fetal adrenal produces cortisol but no detectable aldosterone throu...
Abstract Background Human fetal adrenal glands are highly active and, with the placenta, regulate circulating progesterone, estrogen and corticosteroids in the fetus. At birth... -
Effect of dose and dose rate on temporal γ-H2AX kinetics in mouse blood and s...
Abstract Background Cesium-137 (137Cs) is one of the major and most clinically relevant radionuclides of concern in a radiological dispersal device, “dirty bomb” scenario as... -
Carbon black suppresses the osteogenesis of mesenchymal stem cells: the role ...
Abstract Background The rapid increase in carbon black poses threats to human health. We evaluated the effect of CB (Printex 90) on the osteogenesis of bone-marrow-derived... -
Efficacy and safety of Ding-Kun-Dan for female infertility patients with pred...
Abstract Background Women undergoing in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) who have a predicted poor ovarian response (POR) present a challenge... -
Income differences in screening, incidence, postoperative complications, and ...
Abstract Background The incidence of thyroid cancer (TC) has increased rapidly over the past few decades in Korea. This study investigated whether the TC epidemic has been... -
A randomized controlled trial protocol comparing the feeds of fresh versus fr...
Abstract Background Necrotizing enterocolitis (NEC) is the leading cause of death among preterm infants born at -
Tumor-associated neutrophils induce EMT by IL-17a to promote migration and in...
Abstract Purpose Epithelial to mesenchymal transition (EMT) can contribute to gastric cancer (GC) progression and recurrence following therapy. Tumor-associated neutrophils... -
Distinct immune responses of juvenile and adult oysters (Crassostrea gigas) t...
Abstract Since 2008, massive mortality events of Pacific oysters (Crassostrea gigas) have been reported worldwide and these disease events are often associated with Ostreid... -
Thymic carcinoma metastasize to the small intestine: a case report
Abstract Background Thymic carcinoma is a rare mediastinal neoplasm with a high malignant potential. It often shows pleural invasion and distant metastasis. The metastasis of... -
Comparison of the effects of Crataegus oxyacantha extract, aerobic exercise a...
Abstract Background Adhesion molecules play an important role in the development and progression of coronary atherosclerosis. The aim of this study was comparing the effect of... -
Volumetric optical mapping in early embryonic hearts using light-sheet micros...
Optical mapping (OM) of electrical activity using voltage-sensitive fluorescent dyes is a powerful tool for the investigation of embryonic cardiac electrophysiology. However,... -
Insulinlike Growth Factor (IGF)-1 Administration Ameliorates Disease Manifest...
Abstract Spinal and bulbar muscular atrophy is an X-linked motor neuron disease caused by polyglutamine expansion in the androgen receptor. Patients develop slowly progressive... -
Structured reporting has the potential to reduce reporting times of dual-ener...
Abstract Background In recent years, structured reporting has been shown to be beneficial with regard to report completeness and clinical decision-making as compared to... -
Forkhead Box F1 promotes breast cancer cell migration by upregulating lysyl o...
Abstract Background Epithelial-mesenchymal transition (EMT) increases cell migration and is implicated in cancer cell invasion and metastasis. We have previously described the... -
Evaluation of two collagen conduits and autograft in rabbit sciatic nerve reg...
Abstract Background We compared different surgical techniques for nerve regeneration in a rabbit sciatic nerve gap model using magnetic resonance diffusion tensor imaging (DTI),... -
One size doesn’t fit all: cross-sectional associations between neighborhood w...
Abstract Background Low-income African American adults are disproportionately affected by obesity and are also least likely to engage in recommended levels of physical activity...
