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A bacosides containing Bacopa monnieri extract alleviates allodynia and hyper...
Abstract Background The current therapy of neuropathic pain is inadequate and is limited by the extent of pain relief and the occurrence of dose dependant side effects.... -
Development of a high-throughput screen to identify small molecule enhancers ...
Abstract Background Duchenne muscular dystrophy (DMD) is caused by loss of sarcolemma connection to the extracellular matrix. Transgenic overexpression of the transmembrane... -
Differential expression of Cdk5-phosphorylated CRMP2 following a spared nerve...
Abstract Effective treatment of high-impact pain patients is one of the major stated goals of the National Pain Strategy in the United States. Identification of new targets and... -
Dynamic light sheet generation and fluorescence imaging behind turbid media
Abstract Background Light sheet microscopy became a popular tool allowing fast imaging with reduced out of focus light. However, when light penetrates turbid media such as... -
The association between anemia and falls in community-living women and men ag...
Abstract Background Falls are common among elderly people, and the risk increase with age. Falls are associated with both health and social consequences for the patient, and... -
The Ussing chamber system for measuring intestinal permeability in health and...
Abstract Background The relationship between intestinal epithelial integrity and the development of intestinal disease is of increasing interest. A reduction in mucosal... -
The role of income and occupation in the association of education with health...
Abstract Background The beneficial effects of higher education on healthy aging are generally accepted, but the mechanisms are less well understood. Education may influence... -
An investigation to assess ankle mobility in healthy individuals from the app...
Abstract Background An investigation was undertaken to compare the effect of multi-component compression bandages and compression hosiery kits on individuals’ range of ankle... -
Deciphering how LIP2 and POX2 promoters can optimally regulate recombinant pr...
Abstract Background In recent years, the non-conventional model yeast species Yarrowia lipolytica has received much attention because it is a useful cell factory for producing... -
Interaction according to urinary sodium excretion level on the association be...
Objective: We examined an interaction according to the estimated 24-h urinary sodium excretion on the association between ATP2B1 rs17249754 and incident hypertension. Methods:... -
Ultrasound-guided regional anesthesia simulation: use of meat glue in inexpen...
Abstract Background Ultrasound-guided regional anesthesia (UGRA) is increasingly used by emergency physicians to provide safe and effective pain relief for patients. However,... -
Effects of acute ethanol intoxication in an ovine peritonitis model
Abstract Background Acute ethanol intoxication has been shown to have contrasting effects on outcomes in sepsis. The aim of this study was to explore the effects of acute... -
Initial assessment of femoral proximal fracture and acute hip arthritis using...
Abstract Background Acute hip pain caused by femoral proximal fractures or acute hip arthritis requires imaging for accurate diagnosis. Although pocket-sized ultrasound (PsUS)... -
Air pollution-induced placental epigenetic alterations in early life: a candi...
Particulate matter (PM) exposure during in utero life may entail adverse health outcomes in later-life. Air pollution's adverse effects are known to alter gene expression... -
CYP1A1 methylation mediates the effect of smoking and occupational polycyclic...
Abstract Background Multiple factors, including co-exposure between lifestyle and environmental risks, are important in susceptibility to oxidative DNA damage. However, the... -
New inducible promoter for gene expression and synthetic biology in Yarrowia ...
Abstract Background The oleaginous yeast Yarrowia lipolytica is increasingly used as alternative cell factory for the production of recombinant proteins. At present, several... -
Skin autofluorescence is associated with inappropriate left ventricular mass ...
Abstract Background Enhanced advanced glycation end products deposition within myocardial tissue may cause diastolic dysfunction. However, whether this is related to left... -
Validating self-reporting of hearing-related symptoms against pure-tone audio...
Objective: To validate self-reported hearing-related symptoms among personnel exposed to moderately high occupational noise levels at an obstetrics clinic. Design: Sensitivity,... -
Fiber-based polarization-sensitive OCT for birefringence imaging of the anter...
We demonstrate a prototype system of polarization-sensitive optical coherence tomography (PS-OCT) designed for clinical studies of the anterior eye segment imaging. The system... -
Diagnostic ability of macular ganglion cell asymmetry in Preperimetric Glaucoma
Abstract Background To evaluate the diagnostic ability of macular ganglion cell asymmetry to diagnose preperimetric glaucoma (PPG), using Cirrus spectral domain optical...
