340 items found

Licenses: License Not Specified Tags: 110309 Infectious Diseases 69999 Biological Sciences not elsewhere classified Pharmacology Types: other

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    Food systems transformations, ultra-processed food markets and the nutrition ...

    Abstract Background Attracted by their high economic growth rates, young and growing populations, and increasingly open markets, transnational food and beverage corporations...
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    Prioritising pathogens for the management of severe febrile patients to impro...

    Abstract Background Severe febrile illness without a known source (SFWS) is a challenge for clinicians when deciding how to manage a patient, particularly given the wide...
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    Prescribing pattern of statins for primary prevention of cardiovascular disea...

    Abstract Objective Although most clinical practice guidelines endorsed statin use in type 2 diabetes (T2D) patients for reducing cardiovascular diseases (CVD), little is known...
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    Effects of cigarette smoke on barrier function and tight junction proteins in...

    Abstract Background Airway epithelial barrier function is maintained by the formation of tight junctions (TJs) and adherens junctions (AJs). Inhalation of cigarette smoke causes...
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    Efficacy and safety of everolimus in combination with trastuzumab and paclita...

    Abstract Background The current exploratory analysis was performed to evaluate the efficacy and safety of everolimus for treatment of human epidermal growth factor receptor...
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    Safety and efficacy of nivolumab in combination with sunitinib or pazopanib i...

    Abstract Background Combination treatment with immune checkpoint inhibitors and antiangiogenic drugs has shown encouraging preliminary antitumor activity across various tumor...
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    Baseline characteristics and comorbidities in the CAnadian REgistry for Pulmo...

    Abstract Background The CAnadian REgistry for Pulmonary Fibrosis (CARE-PF) is a multi-center, prospective registry designed to study the natural history of fibrotic interstitial...
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    YY-1224, a terpene trilactone-strengthened Ginkgo biloba, attenuates neurodeg...

    Abstract Background Ginkgo biloba has been reported to possess free radical-scavenging antioxidant activity and anti-inflammatory properties. In our pilot study, YY-1224, a...
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    Failure of target attainment of beta-lactam antibiotics in critically ill pat...

    Abstract Background Early and appropriate antibiotic dosing is associated with improved clinical outcomes in critically ill patients, yet target attainment remains a challenge....
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    Fostering cultural responsiveness in physiotherapy: curricula survey of Austr...

    Abstract Background Developing cultural responsiveness among physiotherapists is considered essential to promote quality and equity in healthcare provision for our culturally...
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    Urinary tract infections in pregnancy in a rural population of Bangladesh: po...

    Abstract Background Urinary tract infection (UTI) in pregnancy, including asymptomatic bacteriuria, is associated with maternal morbidity and adverse pregnancy outcomes,...
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    Gestational weight gain information: seeking and sources among pregnant women

    Abstract Background Promoting healthy gestational weight gain (GWG) is important for preventing obstetric and perinatal morbidity, along with obesity in both mother and child....
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    A systematic review of non-standard dosing of oral anticancer therapies

    Abstract Background The use of oral systemic anticancer therapies (SACT) has increased and led to improved cancer survival outcomes, particularly with the introduction of small...
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    A randomized, 29-day, dose-ranging, efficacy and safety study of daprodustat,...

    Abstract Background Daprodustat is a hypoxia-inducible factor-prolyl hydroxylase inhibitor currently being investigated as a treatment for anemia of chronic kidney disease (CKD)...
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    TNFAIP3 is required for FGFR1 activation-promoted proliferation and tumorigen...

    Abstract Background Although ductal carcinoma in situ (DCIS) is a non-invasive breast cancer, many DCIS lesions may progress to invasive cancer and the genes and pathways...
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    A few antibiotics can represent the total hospital antibiotic consumption

    Abstract Background Appropriate antibiotic use has become an important issue. However, collecting data on the use of all antibiotics in a hospital is difficult without an...
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    Contribution of spinal cord glial cells to L. amazonensis experimental infect...

    Abstract Background The cellular and molecular pathophysiological mecha\nisms of pain processing in neglected parasitic infections such as leishmaniasis remain unknown. The...
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    Influence of wood species on toxicity of log-wood stove combustion aerosols: ...

    Abstract Background Wood combustion emissions have been studied previously either by in vitro or in vivo models using collected particles, yet most studies have neglected...
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    Adrenal suppression in children treated with swallowed fluticasone and oral v...

    Abstract Background Adrenal suppression (AS), a glucocorticoid (GC) side effect associated with significant morbidity, is well described related to inhaled corticosteroid...
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    Development of rapid guidelines: 1. Systematic survey of current practices an...

    Abstract Background Guidelines in the healthcare field generally should contain evidence-based recommendations to inform healthcare decisions. Guidelines often require 2 years...