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Novel γ-Aminobutyric Acid ρ<sub>1</sub> Receptor Antagonists; Synthesis, Phar...
γ-Aminobutyric acid (GABA) analogues based on 4-amino-cyclopent-1-enyl phosphinic acid (34−42) and 3-aminocyclobutane phosphinic acids (51, 52, 56, 57) were investigated in... -
Quaternary Structural Transitions in the DeoR-Type Repressor UlaR Control Tra...
UlaR is a DNA binding protein of the DeoR family of eubacterial transcriptional repressors which maintains the utilization of the l-ascorbate ula regulon in a repressed state.... -
Are Neutral Chloroacetamide Herbicide Degradates of Potential Environmental C...
Although laboratory studies have revealed that many different neutral degradates of chloroacetamide herbicides can form during thermochemical, biological, and photochemical... -
Terminology Registries And Services
This conference poster gives an overview of terminology registries and services. Terminology registries can broadly be classified into registries, repositories, and services. A... -
Alkaline-Earth Metal Mercury Intermetallics <i>A</i><sub>11−<i>x</i></sub>Hg<...
Re-examination of the mercury-rich regions of the Ca−Hg and Sr−Hg phase diagrams has shown that the phases previously identified as “AHg3.6” should be reformulated as... -
A Rational Approach to Minimal High-Resolution Cross-Reactive Arrays
We report a rational approach to the construction of cross-reactive arrays for steroids consisting of five to seven sensors incorporating modified oligonucleotides. The sensors... -
r37980778c78--d1bfb7661c219b26839ddb91e0e85b6b
l-Glycals can be prepared in seven steps from readily available d-glucals, enabling the facile construction of mirror-image carbohydrates such as the l-lactosamine derivative... -
Synthesis of Monodisperse Spiro-Bridged Ladder-Type Oligo-<i>p</i>-phenylenes
Monodisperse spiro-bridged ladder-type oligo-p-phenylenes, which have very rigid backbones, exhibited intensive emissions with very small Stocks shifts, displayed very good... -
r37980778c78--1e13d726e90796f167fd4fd4eacc3a18
Modulation of soluble guanylate cyclase (sGC) activity by nitric oxide (NO) involves two distinct steps. Low-level activation of sGC is achieved by the stoichiometric binding of... -
Iridium-catalyzed borylation of benzene with diboron. Theoretical elucidation...
Iridium-catalyzed borylation of benzene with diboron was theoretically investigated with the DFT method, where an iridium(I) boryl complex, Ir(Beg)(NN) 1, and an iridium(III)... -
Azobenzene-Tethered T7 Promoter for Efficient Photoregulation of Transcription
Azobenzene was additionally introduced into side chain of T7 promoter for the photocontrol of transcription reaction by T7 RNA polymerase (T7 RNAP). When a single azobenzene... -
r37980778c78--e81048fe72032069e4f4d16db36d87a9
The yeast two-hybrid assay has proven to be a powerful method to detect protein−protein interactions as well as to derive genome-wide protein interaction maps. More recently,... -
r37980778c78--e566fd3a81587c206488d7815d43b84f
Simple preparation methods of modified guanidines have been explored as potential chiral superbases. Thus, 3,7,8-trisubstituted and 3,6,7,8-tetrasubstituted... -
Mechanism of Metal Chloride-Promoted Mukaiyama Aldol Reactions
Ab initio calculations (MP2/6-311+G*//B3LYP/6-31G) were employed to investigate the mechanism of metal chloride-promoted Mukaiyama aldol reaction between trihydrosilyl enol... -
Steering S−H and N−H Bond Activation by a Stable N-Heterocyclic Silylene: Dif...
The strikingly different behavior of the ylide-like, N-heterocyclic silylene LSi: (5: L = CH[(CCH2)CMe(NAr)2]; Ar = 2,6-iPrC6H3) versus its LSi→Ni(CO)3 complex 13 to activate... -
r37980778c78--bdadefd750b243dea96ae3fcb10bb89e
We have developed the chemistry for preparing a universal probe and the appropriate nano- and microparticle labels that can be used to do highly selective multiplexed detection... -
Additional file 2: Figure S1. of Expressed alleles of imprinted IGF2, DLK1 an...
a, Distribution of DNA spot centers to CT edge distances for both alleles located outside of CT is shown. For both alleles, the maximal distance found between RNA spot center... -
Mechanistic Studies on Au(I)-Catalyzed [3,3]-Sigmatropic Rearrangements using...
A comparative study of the Au(I)-catalyzed [3,3]-sigmatropic rearrangement of propargylic esters and propargyl vinyl ethers is described. Stereochemically defined cyclopropanes... -
Identification of a Pharmacophore for Thrombopoietic Activity of Small, Non-P...
The invention of a new class of naphtho[1,2-d]imidazole thrombopoietin mimics based on a pharmacophore hypothesis for small-molecule thrombopoietic agonists is discussed.... -
r37980778c78--acde7a20d0b9659e7d1b36d92a65cff2
Oxone is found to be an effective oxidant for the oxidative amidation of aldehydes with anilines to furnish amides in a one-pot process under mechanical milling conditions.
