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r37980778c78--a40d986ef1025d19d9685143933b56e4
Using dendrimers in cancer therapy as nonviral vectors for gene delivery seems promising. The biological performance of a dendrimer-based gene delivery system depends heavily on... -
r37980778c78--b83177d0c6de60e307794c8ade834f8e
l-Fucose, 6-deoxy-l-galactose, is a key component of many important glycoconjugates including the blood group antigens and the LewisX ligands. The biosynthesis of GDP-l-fucose... -
dedup_wf_001--4edd6b37544e4fc6acb3bb4fce0088b7
A major bottleneck for the exploitation of data from the Kepler mission for stellar astrophysics and exoplanet research has been the lack of precise radii and evolutionary... -
r37980778c78--d5ffa792767440d5d3382b0243ed9f91
The compound trimesic acid (H3TMA) with 2,6-bis(4-pyridylmethylene)cyclohexanone (1) was shown to form two-/three-/four-component cocrystals or salts depending on the reaction... -
Catalytic Carbon−Halogen Bond Activation: Trends in Reactivity, Selectivity,...
We have theoretically studied the oxidative addition of all halomethanes CH3X (with X = F, Cl, Br, I, At) to Pd and PdCl-, using both nonrelativistic and... -
r37980778c78--5021c87261f3e825dde9a93ad9814f8e
To develop a novel antipsychotic agent which is an agonist of dopamine (DA) autoreceptors and an antagonist of postsynaptic DA receptors, a series of 7-[4-[4-(substituted... -
Ruthenium-Catalyzed [2 + 2] Cycloadditions of Bicyclic Alkenes with Alkynyl P...
Ruthenium-catalyzed [2 + 2] cycloadditions of bicyclic alkenes with alkynyl phosphonates were investigated. The phosphonate moieties were found to be compatible with the... -
Thermal Degradation of Designed Carbohydrate <i>N</i>-Oxides: A Single Metho...
Thermal Degradation of Designed Carbohydrate N-Oxides: A Single Methodology for the Synthesis of Ketoses, Enol Ethers, and Branched-Chain Sugars from N-Oxides Derived from... -
Anhydrolide Macrolides. 1. Synthesis and Antibacterial Activity of 2,3-Anhydr...
A series of 3-descladinosyl-2,3-anhydro-6-O-methylerythromycin A 11,12-carbamate analogues have been synthesized and evaluated for antibacterial activity. These compounds were... -
Generation and Characterization of Four Dilutions of Diesel Engine Exhaust fo...
Exposure atmospheres for a rodent inhalation toxicology study were generated from the exhaust of a 2000 Cummins ISB 5.9L diesel engine coupled to a dynamometer and operated on a... -
Efficient Synthesis of MUC4 Sialylglycopeptide through the New Sialylation Us...
Sialylation reactions using a new sialyl donor, diethyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-O-β-d-glycero-d-galacto-2-nonulopyranosylonamide phosphite... -
Identification of a Boron-Containing Intermediate in the Boron Tribromide Med...
An alternate reaction mechanism for the boron tribromide mediated deprotection of aryl propargyl ethers based on the isolation of a key boron-containing byproduct is proposed.... -
New Sensitive Fluorophores for Selective DNA Detection
4,7-Disubstituted benzothiadiazoles containing 1-arylethynyl and 4-methoxyphenyl groups are selective photoluminescent “light up” probes to duplex DNA with unprecedented... -
Additional file 1: Figure S1. of Isolation and characterization of chromosoma...
PpCR-1 monomer hunting from the amplified sequence by designated primers of clone 6. Figure S2. PpTR-1 monomer hunting from the amplified sequence by designated primers of clone... -
r37980778c78--fb2c9e56a071472b52b76dc212338718
The convergent total synthesis of brevetoxin B (1) has been achieved. The intramolecular allylation of the O,S-acetal 20, prepared from the α-chlorosulfide 17 and the alcohol 5,... -
r37980778c78--25b81389fc923ee14539f641468ff031
Synthesis and photochemistry of several title compounds 1−3 containing multiple chromophoric systems are described. The Diels−Alder reactions of... -
Sensitive and Convenient Yeast Reporter Assay for High-Throughput Analysis by...
The yeast reporter assay has been widely used in various applications such as detection of endocrine disruptors and analysis of protein−protein interactions by the yeast... -
The Turing Way: Transforming Research with Collaborative Working
Kirstie's slides for her talk at the Advanced Methods for Reproducible Science workshop. -
Reactions of α,α‘-Dihydroxy Ketones with Phosgene. Structural Requirements fo...
α,α‘-Dihydroxy ketones having two OH groups that can come into close proximity react with phosgene in the presence of DMAP to produce 1,3-dioxane-2,5-diones. When covalent... -
Phase-Vanishing Reactions that Use Fluorous Media as a Phase Screen. Facile, ...
In fluorous triphasic reactions, such as bromination of alkenes by dibromine and dealkylation of aromatic ethers by boron tribromide, the middle fluorous phase acts as a liquid...
