-
Anti-malarial treatment outcomes in Ethiopia: a systematic review and meta-an...
Abstract Background Ethiopia is among countries with a high malaria burden. There are several studies that assessed the efficacy of anti-malarial agents in the country and this... -
UK national clinical audit: management of pregnancies in women with HIV
Abstract Background The potential for HIV transmission between a pregnant woman and her unborn child was first recognized in 1982. Since then a complex package of measures to... -
Comparison of anti-malarial drugs efficacy in the treatment of uncomplicated ...
Abstract Background Artemisinin-based combination therapy (ACT) and novel drug combinations are available and used in African countries to treat uncomplicated malaria. Network... -
Pilot study comparing the Childhood Arthritis & Rheumatology Research All...
Abstract Objectives To assess the feasibility of studying the comparative effectiveness of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) consensus treatment... -
Estimating the cost-effectiveness of daclatasvir + sofosbuvir versus sofosbuv...
Abstract Background As treatments for chronic hepatitis C are moving away from interferon-containing regimens, the most appropriate allocation of resources to higher cost,... -
Development of a core outcome set for clinical trials in facial aging: study ...
Abstract Background Facial aging is a concern for many patients. Wrinkles, loss of volume, and discoloration are common physical manifestations of aging skin. Genetic heritage,... -
Differential expression of E-type prostanoid receptors 2 and 4 in microglia s...
Abstract Background Cyclooxygenase-2 (COX-2) is induced under inflammatory conditions, and prostaglandin E2 (PGE2) is one of the products of COX activity. PGE2 has pleiotropic... -
Controlling schistosomiasis with praziquantel: How much longer without a viab...
Abstract The current approach of morbidity control of schistosomiasis, a helminth disease of poverty with considerable public health and socioeconomic impact, is based on... -
Retrospective case-control non-inferiority analysis of intravenous lidocaine ...
Abstract Background Enhanced recovery after surgery (ERAS) programs typically utilizes multi-modal analgesia to reduce perioperative opioid consumption. Systemic lidocaine is... -
Variability of Uncrossmatched Blood Use by Helicopter EMS Programs in the Uni...
Study Objective: Some helicopter emergency medical services (HEMS) maintain an independent supply of blood for use during transport, although practice is variable and not well... -
A new prescription model for regional citrate anticoagulation in therapeutic ...
Abstract Background Regional citrate anticoagulation (RCA) is proposed for various extracorporeal purification techniques to overcome the risk of bleeding that might result from... -
Coverage of harm reduction services and HIV infection: a multilevel analysis ...
Abstract Background Since 2003, a harm reduction program for injecting drug users has been rolled out countrywide in China. It entails services for condom promotion, a needle... -
MyD88-dependent pro-interleukin-1β induction in dendritic cells exposed to fo...
Abstract Background Dendritic cells (DCs) are specialized first-line sensors of foreign materials invading the organism. These sentinel cells rely on pattern recognition... -
The effects of interventions on quality of life, morbidity and consultation f...
Background Patients visiting their GPs exceptionally often (frequent attenders, FAs) have high rates of somatic disease, emotional distress, psychiatric illnesses and social... -
The efficacy of varenicline in achieving abstinence among waterpipe tobacco s...
Abstract Background Waterpipe tobacco smoking has increased among youth across the globe including in the US, and it continues as a common and traditional form of smoking... -
Approval status and evidence for WHO essential medicines for children in the ...
Abstract Background The WHO Model List of Essential Medicines for Children (EMLc) covers medicines for globally high-burden diseases. Regulatory approval in high-income... -
The effect of the Xpert MTB/RIF test on the time to MDR-TB treatment initiati...
Abstract Background There are significant delays in initiation of multidrug-resistant tuberculosis (MDR –TB) treatment. The Xpert MTB/RIF test has been shown to reduce the time... -
Household beliefs about malaria testing and treatment in Western Kenya: the r...
Abstract Background Although use of malaria diagnostic tests has increased in recent years, health workers often prescribe anti-malarial drugs to individuals who test negative... -
The impact of the time of drug administration on the effectiveness of combine...
Abstract Background Hypercholesterolemia is one of the main risk factors for cardiovascular disease. The first line treatment for hypercholesterolemia is statin therapy. When... -
Cost-effectiveness of antibiotic treatment strategies for community-acquired ...
Abstract Background To determine the cost-effectiveness of strategies of preferred antibiotic treatment with beta-lactam/macrolide combination or fluoroquinolone monotherapy...
