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Twenty-five years of optical coherence tomography: the paradigm shift in sens...
Optical coherence tomography (OCT) has become one of the most successful optical technologies implemented in medicine and clinical practice mostly due to the possibility of... -
Patternable particle microarray utilizing controllable particle delivery
Abstract In this study, we demonstrate an on-demand delivering and sequential arraying of single microparticles utilizing multiple pneumatic pressure-driven elastomer valves and... -
A method for sensitivity analysis to assess the effects of measurement error ...
Abstract Background Measurement error in self-reported dietary intakes is known to bias the association between dietary intake and a health outcome of interest such as risk of a... -
Respiration activity monitoring system for any individual well of a 48-well m...
Abstract Background Small-scale micro-bioreactors have become the cultivation vessel of choice during the first steps of bioprocess development. They combine high cultivation... -
Integrative assessment of brain and bone invasion in meningioma patients
Abstract Background Various prognostic factors have been suggested in meningioma patients including WHO grading, brain invasion and bone involvement, for instance. Brain... -
One–shot phase stepping with a pulsed laser and modulation of polarization: a...
For applications involving time varying optical phase distributions, fast cameras and/or pulsed lasers have to be used. To apply phase–shifting interferometry techniques (PSI)... -
Fat mass and fat distribution are associated with low back pain intensity and...
Abstract Background Determining the association between body composition and low back pain (LBP) will improve our understanding of the mechanisms by which obesity affects LBP,... -
Evaluation of EMG pattern recognition for upper limb prosthesis control: a ca...
Abstract Background Although electromyogram (EMG) pattern recognition (PR) for multifunctional upper limb prosthesis control has been reported for decades, the clinical benefits... -
Ultracompact metasurface in-line polarimeter
In-line polarimeters perform nondestructive polarization measurements of optical signals, and play a critical role in monitoring and controlling the polarization environment in,... -
A novel transcription factor specifically regulates GH11 xylanase genes in Tr...
Abstract Background The filamentous fungus Trichoderma reesei is widely utilized in industry for cellulase production, but its xylanase activity must be improved to enhance the... -
Study of serious adverse drug reactions using FDA-approved drug labeling and ...
Abstract Background Adverse Drug Reactions (ADRs) are of great public health concern. FDA-approved drug labeling summarizes ADRs of a drug product mainly in three sections,... -
Readability of patient information and consent documents in rheumatological s...
Abstract Background Before participation in medical research an informed consent must be obtained. This study investigates whether the readability of patient information and... -
Module and individual domain deletions of NRPS to produce plipastatin derivat...
Abstract Background Plipastatin, an antifungal lipopeptide, is synthesized by a non-ribosomal peptide synthetase (NRPS) in Bacillus subtilis. However, little information is... -
Three-dimensional Dammann array
We demonstrate a scheme that can produce a three-dimensional (3D) focus spot array in a 3D lattice structure, called a 3D Dammann array, in focal region of an objective. This 3D... -
Thermal expansion feedback for wave-front shaping
Focusing inside scattering media is a challenging task with a variety of applications in biomedicine. State of the art methods mostly require invasive feedback inside or behind... -
Unfavourable risk factor control after coronary events in routine clinical pr...
Abstract Background Risk factor control after a coronary event in a recent European multi-centre study was inadequate. Patient selection from academic centres and low... -
The putative β-glucosidase BGL3I regulates cellulase induction in Trichoderma...
Abstract Background The filamentous fungus Trichoderma reesei (anamorph of Hypocrea jecorina) displays increased cellulase expression while growing on inducers such as lactose... -
Fecal metatranscriptomics of macaques with idiopathic chronic diarrhea reveal...
Abstract Background Idiopathic chronic diarrhea (ICD) is a common cause of morbidity and mortality among juvenile rhesus macaques. Characterized by chronic inflammation of the... -
Prediction of advanced colonic neoplasm in symptomatic patients: a scoring sy...
Abstract Background Fast-track colonoscopy to detect patients with colorectal cancer based on high-risk symptoms is associated with low sensitivity and specificity. The aim was... -
Reference genome and comparative genome analysis for the WHO reference strain...
The BCG live attenuated TB vaccine is one of the oldest and most widely used vaccines in human medicine. Each year, BCG vaccines are administered to over 100 million newborns...