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Antioxidant and Antiapoptotic effect of aqueous extract of Pueraria tuberosa ...
Abstract Background Oxidative stress and renal apoptosis play a significant role in the progression of diabetic nephropathy. The tubers of Pueraria tuberosa (Roxb. ex Willd.)... -
Inhibition of Salmonella Typhimurium adhesion, invasion, and intracellular su...
Abstract Salmonella enterica serovar Typhimurium infects intestinal epithelia and macrophages, which is prevented by inhibiting adhesion and cell invasion. This study aimed to... -
Multiphoton in vivo imaging with a femtosecond semiconductor disk laser
We use an ultrafast diode-pumped semiconductor disk laser (SDL) to demonstrate several applications in multiphoton microscopy. The ultrafast SDL is based on an optically pumped... -
Asthmatic bronchial epithelial cells promote the establishment of a Hyalurona...
Abstract Background Airway inflammation is a hallmark of asthma. Alterations in extracellular matrix (ECM) hyaluronan (HA) content have been shown to modulate the recruitment... -
Heat shock pretreatment improves mesenchymal stem cell viability by heat shoc...
Abstract Background Bone marrow mesenchymal stem cells (BMSCs) can partially repair chemotherapy-induced ovarian damage. However, low survival rate after transplantation hampers... -
Efficacy, tolerability and safety of darbepoetin alfa injection for the treat...
Abstract Background Darbepoetin alfa (DA-α) is a long-acting erythropoiesis-stimulating glycoprotein which has half-life three-fold longer than that of Erythropoietin alfa... -
Umbilical cord/placenta-derived mesenchymal stem cells inhibit fibrogenic act...
Abstract Background The lack of anti-fibrotic agents targeting intestinal fibrosis is a large unmet need in inflammatory bowel diseases, including Crohn’s disease and ulcerative... -
Effects of hypoxia and hyperoxia on the differential expression of VEGF-A iso...
Abstract Dysregulation of VEGF-A bioavailability has been implicated in the development of lung injury/fibrosis, exemplified by Idiopathic Pulmonary Fibrosis (IPF). VEGF-A is a... -
Promoter methylation inhibits expression of tumor suppressor KIBRA in human c...
Abstract Background KIBRA has been suggested as a key regulator of the Hippo signaling pathway, regulating organ size, cell contact inhibition, tissue regeneration as well as... -
Evaluation of human primary intestinal monolayers for drug metabolizing capab...
Abstract Background The intestinal epithelium is a major site of drug metabolism in the human body, possessing enterocytes that house brush border enzymes and phase I and II... -
Acute kidney injury and mild therapeutic hypothermia in patients after cardio...
Abstract Background The aim of this study was to investigate the influence of mild therapeutic hypothermia (MTH) on the incidence of and recovery from acute kidney injury (AKI).... -
TGFβ1-induced SMAD2/3 and SMAD1/5 phosphorylation are both ALK5-kinase-depend...
Abstract Background Dysregulated transforming growth factor β (TGFβ) signaling is implicated in osteoarthritis development, making normalizing TGFβ signaling a possible therapy....
