-
Medication therapy strategies for the coronavirus disease 2019 (COVID-19): re...
The coronavirus disease 2019 (COVID-19) pandemic has spread globally since it outbroke in December 2019. The urgent pandemic presents an unprecedented challenge to develop and... -
Burden of disease and costs associated with type 2 diabetes in emerging and e...
To estimate the clinical and economic burden of type 2 diabetes (T2D) in established (EST) and emerging markets (EMG). Three systematic literature reviews were conducted in... -
Systematic literature review of the epidemiology and clinical burden of chron...
We conducted a systematic literature review (SLR) to determine the epidemiology and clinical burden of chronic rhinosinusitis with nasal polyps (CRSwNP) and to describe how the... -
dedup_wf_001--112619b9a890dbb702d8f88e294728a0
We systematically reviewed adverse events (AEs) for ocrelizumab for multiple sclerosis (MS). We searched Medline, Embase, Web of Science, and Toxicology Data Network-TOXLINE... -
Level of glycemic control among US type 2 diabetes mellitus patients on dual ...
To assess the level of glycemic control among type 2 diabetes patients on sodium-glucose cotransporter 2 inhibitor (SGLT2i) and metformin dual therapy. Observational,... -
Statistical considerations for medication adherence research
OBJECTIVE Medication non-adherence is a widespread problem and has been known to be associated with worse health outcomes and increased healthcare costs. Although many measures... -
Renal complications in COVID-19: a systematic review and meta-analysis
Emerging data suggest that coronavirus disease 2019 (COVID-19) has extrapulmonary manifestations but its renal manifestations are not clearly defined. We aimed to evaluate renal... -
Cost-effectiveness of pembrolizumab with axitinib as first-line treatment for...
Objective: Pembrolizumab/axitinib significantly prolonged overall survival (OS) and progression-free survival (PFS) and increased objective response rate versus sunitinib in the... -
dedup_wf_001--a35e03ea4a8f433445518894738e3a56
Emergency Departments (ED) are rapidly becoming an important location for initiation of buprenorphine (EDBUP) for the treatment of opioid use disorder (OUD). Previous... -
dedup_wf_001--b2aea697ee420d2a6a886a8155e8b204
The β-D-Mannuronic acid (M2000) as a novel immunosuppressive drug, patented (PCT/EP2017/067920), has shown positive effects in experimental model of multiple sclerosis (MS). In... -
Patient preferences and predicted relative uptake for targeted therapies in m...
Objective Ras wild-type metastatic colorectal cancers (mCRC) may be treated with anti-vascular endothelial growth factor (VEGF) or anti-epidermal growth factor receptor (EGFR)... -
dedup_wf_001--34c2bd16003a978286e2ebb69d938373
Electronic dance music (EDM) party attendees are at high risk for drug use. However, little is known regarding the extent of underreporting of drug use in this population, in... -
dedup_wf_001--509307ac0c6fdddd3073c05efaab8f8e
Marketing authorization holder (MAH)-sponsored patient support programs (PSPs) are a major source of adverse event (AE) reports. The impact of reports from PSPs on the ability... -
Respiratory depression following medications for opioid use disorder (MOUD)-a...
Medications for opioid use disorder (MOUD) including buprenorphine is recommended for patients with opioid use disorders. We sought to evaluate the frequencies of respiratory... -
Healthcare resource utilization and costs associated with postpartum depressi...
Objective: To quantify the economic burden of postpartum depression (PPD) that accrues to commercially insured households in the year following childbirth. Methods:... -
Genetic factors in anthracycline-induced cardiotoxicity in patients treated f...
Cardiovascular diseases are the main cause of treatment-related morbidity and mortality in childhood cancer patients. Anthracyclines, one of the most common chemotherapeutic... -
Verification of the hemolysis index measurement: imprecision, accuracy, measu...
Automated spectrophotometric measurement of hemolysis index (HI) allows rapid and cost-effective assessment of hemolysis interference. We evaluated the analytical performance of... -
Impact of immunogenicity on efficacy and tolerability of tumour necrosis fact...
SB4, SB2, and SB5 are biosimilars of etanercept (ETN), infliximab (INF), and adalimumab (ADA), respectively. This pooled analysis evaluated the immunogenicity of these... -
Pamidronate in chronic non-bacterial osteomyelitis:a randomized, double-blind...
Objective: This is the first randomized double-blinded, placebo-controlled pilot trial to investigate the efficacy of pamidronate in reducing radiological and clinical disease... -
Immune-mediated inflammatory disease patients' preferences in adverse drug re...
Objectives: Patient-reported outcomes (PROs) are increasingly used in studies and medical practice to obtain information on patients’ perspectives toward their treatment or...