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Distinct binding and signaling activity of Acthar Gel compared to other melan...
To compare the binding and agonistic activity of Acthar® Gel and synthetic melanocortin receptor (MCR) agonists and examine how the activity of select agonists affects the in... -
Datumetine exposure alters hippocampal neurotransmitters system in C57BL/6 mice
Our previous study showed that datumetine modulates NMDAR activity with long term exposure leading to memory deficit and altered NMDAR signaling. We aim to explore the... -
TNFAIP8L2/TIPE2 impairs autolysosome reformation via modulating the RAC1-MTOR...
Macroautophagy/autophagy is an evolutionarily conserved process that involves the selective degradation of cytoplasmic components within lysosomes in response to starvation.... -
Military occupation as a moderator between combat exposure and posttraumatic ...
Military occupational designations are standardized classifications that help define and convey a service member’s expected duties and responsibilities. The present study... -
An appraisal of pivotal evaluation designs in validating noninvasive biomarke...
An appraisal of pivotal evaluation designs in validating noninvasive biomarkers for head and neck cancer detection -
Cytotoxicity and antibacterial activity of scutellarein and carajurone-enrich...
The hydroethanolic extract obtained from the dry leaves of Fridericia chica (HEFc) underwent several fractionations by different chromatographic techniques. The ethyl acetate... -
E-waste legislation in the US: An analysis of the disparate design and result...
Electronic waste management in the US has been characterized as ‘inconsistent’, ‘disparate’, and a ‘patchwork’. While there is currently no federal leadership on the regulation... -
Impact of differential and time-dependent autophagy activation on therapeutic...
Activation of macroautophagy/autophagy, a key mechanism involved in the degradation and removal of aggregated proteins, can successfully reverse Huntington disease phenotypes in... -
dedup_wf_001--76d6c0849b62c1fb0e912d7290bfa4ad
Latinos are heavily affected with childhood asthma. Little is known about epigenetic mechanisms of asthma in Latino youth. We conducted a meta-analysis of two epigenome-wide... -
Expression of ADR-α1, 2 and ADR-β2 in cumulus cell culture of infertile women...
Alpha and beta-adrenoceptors (ADR-α1, 2, and β2) play a regulatory role in the folliculogenesis and steroidogenesis in the ovarian follicles. This study aimed to measure these... -
Methylation Status of VDR Gene and its Association with Vitamin D Status and ...
Deficiency in circulatory vitamin D level and vitamin D receptor DNA methylation could be associated with weakened innate immune response and increased susceptibility to... -
Peregrine falcon egg pollutants
ABSTRACTThe role of the peregrine falcon (Falco peregrinus) as a bioindicator for the accumulation of organohalogen compounds and other persistent organic pollutants has been... -
Seasonal distribution and diversity of ground-active arthropods between shrub...
We examined the ground-active arthropods using pitfall trapping beneath Hammada scoparia and Zygophyllum dumosum shrubs and in adjacent open spaces in wet winter, short spring,... -
Molecular mechanism of microRNA-21 promoting Schwann cell proliferation and a...
At present, the functional recovery after nerve injury is not satisfactory in clinical practice. The aim of this study was to explore the molecular mechanism of miR-21 promoting... -
Pamidronate in chronic non-bacterial osteomyelitis:a randomized, double-blind...
Objective: This is the first randomized double-blinded, placebo-controlled pilot trial to investigate the efficacy of pamidronate in reducing radiological and clinical disease... -
Responses of the Mitochondrial Respiratory System to Low Temperature in Plants
ABSTRACTLow-temperature (LT) stress induces significant changes to plant cells including perturbations of various physio-biochemical and metabolic processes, which impact... -
Comparison between insulin degludec/liraglutide treatment and insulin glargin...
ABSTRACTAim: To evaluate the efficacy and adverse effects of IDegLira and IGlarLixi treatment and to perform a comparison between two strategies.Methods: The registration number... -
Study of the controversial resveratrol that interact with the endogenous glut...
Found in various natural food products, many in vitro evidence indicated that resveratrol (RES) has been linked to neuroprotective and cardioprotective effects and prevent... -
Association of PC and AT levels in the early phase of STEMI treated with pPCI...
To examine a relationship between protein C (PC) and antithrombin III (AT III) activities with ejection fraction of left ventricle (EFLV), in the early phase of acute... -
miR-296-5p inhibits IL-1β-induced apoptosis and cartilage degradation in huma...
Osteoarthritis (OA) is characterized by apoptosis of chondrocytes and an imbalance of extracellular matrix (ECM) synthesis and catabolism. Emerging evidence has demonstrated...
