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Economic evaluation of nivolumab combined with ipilimumab in the first-line t...
The objective of this study was to evaluate the cost-effectiveness of nivolumab in combination with ipilimumab (nivo + ipi) compared to current therapeutic alternatives in... -
Medication therapy strategies for the coronavirus disease 2019 (COVID-19): re...
The coronavirus disease 2019 (COVID-19) pandemic has spread globally since it outbroke in December 2019. The urgent pandemic presents an unprecedented challenge to develop and... -
The economic burden of common adverse events associated with metastatic color...
Aims: Adverse events (AEs) associated with treatments for metastatic colorectal cancer (mCRC) may compromise the course of treatment, impact quality-of-life, and increase... -
Systematic literature review of the epidemiology and clinical burden of chron...
We conducted a systematic literature review (SLR) to determine the epidemiology and clinical burden of chronic rhinosinusitis with nasal polyps (CRSwNP) and to describe how the... -
Association of tenofovir disoproxil fumarate exposure with chronic kidney dis...
Tenofovir disoproxil fumarate (TDF)-based regimens have been associated with impaired kidney function and loss of bone mineral density among patients living with HIV (PLWH). We... -
dedup_wf_001--b2aea697ee420d2a6a886a8155e8b204
The β-D-Mannuronic acid (M2000) as a novel immunosuppressive drug, patented (PCT/EP2017/067920), has shown positive effects in experimental model of multiple sclerosis (MS). In... -
Expression of ADR-α1, 2 and ADR-β2 in cumulus cell culture of infertile women...
Alpha and beta-adrenoceptors (ADR-α1, 2, and β2) play a regulatory role in the folliculogenesis and steroidogenesis in the ovarian follicles. This study aimed to measure these... -
The influence of driving anger on truck drivers’ speeding behavior in Serbia:...
OBJECTIVE Speeding behavior is recognized as one of the three main causes of risk on the roads and the most frequent ordinary violation among truck drivers. The study reported... -
Does it pay to lobby? Examining the link between firm lobbying and firm profi...
Does firm lobbying in the EU increase firm profitability? While there is a well-established literature on this issue in the US context, existing EU studies have overlooked this... -
Genetic factors in anthracycline-induced cardiotoxicity in patients treated f...
Cardiovascular diseases are the main cause of treatment-related morbidity and mortality in childhood cancer patients. Anthracyclines, one of the most common chemotherapeutic... -
Factors associated with prolonged time to treatment failure with fulvestrant ...
Objective: The JBCRG-C06 Safari study showed that earlier fulvestrant 500 mg (F500) use, a longer time from diagnosis to F500 use, and no prior palliative chemotherapy were... -
Genkwalathins A and B, new lathyrane-type diterpenes from <i>Daphne genkwa</i>
Screening for new natural anti-neuroinflammatory compounds was performed with the traditional folk medicine Genkwa Flos, which potently inhibited nitric oxide (NO) production by... -
Cost utility analysis of tisagenlecleucel vs salvage chemotherapy in the trea...
Background: Patients with relapsed or refractory diffuse large B-cell lymphoma (r/r DLBCL) have limited treatment options and poor prognoses. Tisagenlecleucel, a chimeric... -
Impact of immunogenicity on efficacy and tolerability of tumour necrosis fact...
SB4, SB2, and SB5 are biosimilars of etanercept (ETN), infliximab (INF), and adalimumab (ADA), respectively. This pooled analysis evaluated the immunogenicity of these... -
Pamidronate in chronic non-bacterial osteomyelitis:a randomized, double-blind...
Objective: This is the first randomized double-blinded, placebo-controlled pilot trial to investigate the efficacy of pamidronate in reducing radiological and clinical disease... -
dedup_wf_001--2a0036ce8c94364642f4ee2734a44384
Dravet syndrome (DS), a prototypic developmental and genetic epileptic encephalopathy (DEE), is characterized by an early onset of treatment-refractory seizures, together with... -
Effect of Diamond-like Carbon Coating on Preventing the Ingress of Hydrogen i...
The failure of moving mechanical components is often accompanied by hydrogen embrittlement caused by hydrogen diffusion in steel. One considerable mechanism for hydrogen... -
Mini-Batch Metropolis–Hastings With Reversible SGLD Proposal
Traditional Markov chain Monte Carlo (MCMC) algorithms are computationally intensive and do not scale well to large data. In particular, the Metropolis–Hastings (MH) algorithm...
