30 items found

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    Erratum to: Pain management strategies for neuropathic pain in Fabry disease ...

    Erratum to: Pain management strategies for neuropathic pain in Fabry disease - a systematic review
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    Glycaemic control targets after traumatic brain injury: a systematic review a...

    Abstract Background Optimal glycaemic targets in traumatic brain injury (TBI) remain unclear. We performed a systematic review and meta-analysis of randomised controlled trials...
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    Twenty-five years of optical coherence tomography: the paradigm shift in sens...

    Optical coherence tomography (OCT) has become one of the most successful optical technologies implemented in medicine and clinical practice mostly due to the possibility of...
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    Defining the clinical pathway in cochrane diagnostic test accuracy reviews

    Abstract Background The value of a medical test depends on the context in which it might be used. Ideally, questions, results and conclusions of a diagnostic test accuracy (DTA)...
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    Ethical aspects of sudden cardiac arrest research using observational data: a...

    Abstract Sudden cardiac arrest (SCA) accounts for half of all cardiac deaths in Europe. In recent years, large-scale SCA registries have been set up to enable observational...
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    A systematic review to investigate the measurement properties of goal attainm...

    Abstract Background One of the main challenges for drug evaluation in rare diseases is the often heterogeneous course of these diseases. Traditional outcome measures may not be...
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    Design constraints of optical parametric chirped pulse amplification based on...

    Chirped quasi-phase-matching (QPM) gratings offer efficient, ultra-broadband optical parametric chirped pulse amplification (OPCPA) in the mid-infrared as well as other spectral...
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    Descriptors for unprofessional behaviours of medical students: A systematic r...

    Abstract Background Developing professionalism is a core task in medical education. Unfortunately, it has remained difficult for educators to identify medical students’...
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    Risk factors for delirium after on-pump cardiac surgery: a systematic review

    Abstract Introduction As evidence-based effective treatment protocols for delirium after cardiac surgery are lacking, efforts should be made to identify risk factors for...
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    The COMET Handbook: Version 1.0

    Abstract The selection of appropriate outcomes is crucial when designing clinical trials in order to compare the effects of different interventions directly. For the findings to...
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    Systematic mapping review of the factors influencing dietary behaviour in eth...

    Abstract Background Europe has a growing population of ethnic minority groups whose dietary behaviours are potentially of public health concern. To promote healthier diets, the...
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    Communicating with conscious and mechanically ventilated critically ill patie...

    Abstract Background Ventilator-dependent patients in the ICU often experience difficulties with one of the most basic human functions, namely communication, due to intubation....
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    A review of reviews on principles, strategies, outcomes and impacts of resear...

    Abstract Background Conducting research in partnership with stakeholders (e.g. policy-makers, practitioners, organisations, patients) is a promising and popular approach to...
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    Assessment of fluid responsiveness in spontaneously breathing patients: a sys...

    Patients who increase stoke volume or cardiac index more than 10 or 15% after a fluid challenge are usually considered fluid responders. Assessment of fluid responsiveness prior...
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    Systematic review of clinical practice guidelines recommendations about prima...

    Abstract Background Clinical care for older adults is complex and represents a growing problem. They are a diverse patient group with varying needs, frequent presence of...
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    Cognitive functioning in patients with classical galactosemia: a systematic r...

    Abstract Background Patients with the metabolic disorder classical galactosemia suffer from long-term complications despite a galactose-restricted diet, including a below...
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    Use of theory to plan or evaluate guideline implementation among physicians: ...

    Abstract Background Guidelines support health care decision-making and high quality care and outcomes. However, their implementation is sub-optimal. Theory-informed, tailored...
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    Microcirculatory perfusion disturbances following cardiopulmonary bypass: a s...

    Abstract Background Microcirculatory perfusion disturbances are associated with increased morbidity and mortality in patients undergoing cardiac surgery with cardiopulmonary...
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    Rational and design of an individual participant data meta-analysis of spinal...

    Abstract Background Chronic low back pain (LBP) is the leading cause of pain and disability, resulting in a major socioeconomic impact. The Cochrane Review which examined the...
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    Risk factors for necrotizing enterocolitis in neonates: a systematic review o...

    Abstract Background Necrotizing enterocolitis (NEC) is a severe multifactorial disease in preterm neonates associated with high morbidity and mortality. Better insight into...