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Distinct binding and signaling activity of Acthar Gel compared to other melan...
To compare the binding and agonistic activity of Acthar® Gel and synthetic melanocortin receptor (MCR) agonists and examine how the activity of select agonists affects the in... -
SUMO conjugation regulates immune signalling
Post-translational modifications (PTMs) are critical drivers and attenuators for proteins that regulate immune signalling cascades in host defence. In this review, we explore... -
Cytotoxicity and antibacterial activity of scutellarein and carajurone-enrich...
The hydroethanolic extract obtained from the dry leaves of Fridericia chica (HEFc) underwent several fractionations by different chromatographic techniques. The ethyl acetate... -
Tetrazoloquinoline-1,2,3-Triazole Derivatives as Antimicrobial Agents: Synthe...
In search of new active molecules, a small focused library of tetrazoloquinoline-based 1,2,3-triazoles has been efficiently prepared via click chemistry approach. Several... -
Expression of ADR-α1, 2 and ADR-β2 in cumulus cell culture of infertile women...
Alpha and beta-adrenoceptors (ADR-α1, 2, and β2) play a regulatory role in the folliculogenesis and steroidogenesis in the ovarian follicles. This study aimed to measure these... -
Seasonal distribution and diversity of ground-active arthropods between shrub...
We examined the ground-active arthropods using pitfall trapping beneath Hammada scoparia and Zygophyllum dumosum shrubs and in adjacent open spaces in wet winter, short spring,... -
Clofibric acid removal by ion exchange using a magnetic ion exchange resin: e...
In this study, a commercial magnetic ion exchange (MIEX) resin was used for the removal of clofibric acid (CA), one of the most persistent pharmaceutical active compounds... -
miR-296-5p inhibits IL-1β-induced apoptosis and cartilage degradation in huma...
Osteoarthritis (OA) is characterized by apoptosis of chondrocytes and an imbalance of extracellular matrix (ECM) synthesis and catabolism. Emerging evidence has demonstrated... -
RNA secondary structure at the transcription start site influences EBOV trans...
Ebola virus (EBOV) RNA has the potential to form hairpin structures at the transcription start sequence (TSS) and reinitiation sites of internal genes, both on the genomic and... -
RETRACTED ARTICLE: Structure revision of aspergicin by the crystal structure ...
AbstractThe structure of aspergicin (1), an antibacterial alkaloid produced by co-culture of two marine-derived mangrove epiphytic fungi, were revised by the co-occurring isomer... -
dedup_wf_001--a66673170c588b96a033e52307ed883a
Lavandula angustifolia Mill. (lavender) and Origanum heracleoticum L. (greek oregano) are aromatic plants used in traditional medicine for relief of convulsion, anxiety,... -
Long-read sequencing uncovers a complex transcriptome topology in varicella z...
Abstract Background Varicella zoster virus (VZV) is a human pathogenic alphaherpesvirus harboring a relatively large DNA molecule. The VZV transcriptome has already been...