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Identifying targets for antibiotic stewardship interventions through analysis...
Abstract Background In order to change antibiotic prescribing behaviour, we need to understand the prescribing process. The aim of this study was to identify targets for... -
Survey on medication information literacy and influencing factors among pregn...
Background: The use of medication during pregnancy is very common. Medication safety has been a great concern among pregnant women and is highly influenced by women’s medication... -
Real world experience of patients with amyotrophic lateral sclerosis (ALS) in...
Background: Treatment of spasticity poses a major challenge in amyotrophic lateral sclerosis (ALS) patient management. Delta-9-tetrahydrocannabinol (THC):cannabidiol (CBD)... -
A systematic literature review of reviews on techniques for physical activity...
Abstract The links between increased participation in Physical Activity (PA) and improvements in health are well established. As this body of evidence has grown, so too has the... -
The efficacy of varenicline in achieving abstinence among waterpipe tobacco s...
Abstract Background Waterpipe tobacco smoking has increased among youth across the globe including in the US, and it continues as a common and traditional form of smoking... -
Prioritising pathogens for the management of severe febrile patients to impro...
Abstract Background Severe febrile illness without a known source (SFWS) is a challenge for clinicians when deciding how to manage a patient, particularly given the wide... -
Influence of genetic variants on toxicity to anti-tubercular agents: a system...
MR is supported partly by Liverpool Reviews and Implementation Group (LRiG), based on funding from the National Institute for Health Research Health Technology Assessment... -
A specific synbiotic-containing amino acid-based formula in dietary managemen...
Here we report follow-up data from a double-blind, randomized, controlled multicenter trial, which investigated fecal microbiota changes with a new amino acid-based formula... -
Confirming the factor structure of a generic quality of life instrument among...
Abstract Background Quality of life (QoL) is a patient-reported outcome of increasing importance in the substance use disorder (SUD) treatment field, and impaired QoL may be an... -
Seeking adverse effects in systematic reviews of orthodontic interventions: P...
Abstract Background Before implementing healthcare interventions, clinicians need to weigh the beneficial and adverse effects of interventions. However, a large body of evidence... -
Cord blood DNA methylation reflects cord blood C-reactive protein levels but ...
Abstract Background Prenatal inflammation has been proposed as an important mediating factor in several adverse pregnancy outcomes. C-reactive protein (CRP) is an inflammatory... -
Sitagliptin does not reduce the risk of cardiovascular death or hospitalizati...
Abstract Background To examine the effects of the DPP-4i sitagliptin on CV outcomes during and after incident MI in the Trial... -
Scaling up strategies of the chronic respiratory disease programme of the Eur...
Abstract Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care... -
Predictors of delayed culture conversion among Ugandan patients
Abstract Background Estimates of month-2 culture conversion, a proxy indicator of tuberculosis (TB) treatment efficacy in phase-2 trials can vary by culture-type and... -
Comparative efficacy between atorvastatin and rosuvastatin in the prevention ...
© 2019 The Author(s). Background: There is no randomized clinical trials with recurrence of atherosclerotic cardiovascular disease (ASCVD) as a major outcome with rosuvastatin.... -
Applying GRADE-CERQual to qualitative evidence synthesis findings: introducti...
Abstract The GRADE-CERQual (‘Confidence in the Evidence from Reviews of Qualitative research’) approach provides guidance for assessing how much confidence to place in findings... -
Differential contractile response of critically ill patients to neuromuscular...
BACKGROUND: Neuromuscular electrical stimulation (NMES) has been investigated as a preventative measure for intensive care unit-acquired weakness. Trial results remain... -
The selective peroxisome proliferator-activated receptor alpha modulator (SPP...
Abstract In the era of precision medicine, treatments that target specific modifiable characteristics of high-risk patients have the potential to lower further the... -
Pharmacological pain relief and fear of childbirth in low risk women; seconda...
Abstract Background Fear of childbirth may reduce the womens’ pain tolerance during labour and may have impact on the mother-infant interaction. We aimed to assess (1) the... -
Introduction of a standardised protocol, including systematic use of tranexam...
Abstract Background Bleeding is an important cause of death in trauma victims. In 2010, the CRASH-2 study, a multicentre randomized control trial on the effect of tranexamic...
